2. Peptides
  3. Peptide and Derivatives
  4. Peptides for Drug Delivery
  5. Peptide Linkers

Peptide Linkers

Custom Peptide Synthesis

Peptide linkers are short peptides used to connect functional molecules, and are often used to design fused proteins and conjugates such as ADCs and PDCs.

Peptide Linkers (26):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P10736A
    AMG133 peptide payload TFA 99.70%
    AMG133 peptide payload TFA is a GLP-1 analog agonist peptide. AMG133 peptide payload TFA potently activates GLP-1R and exhibits weight loss and metabolic improvement activities. AMG133 peptide payload TFA can be used for the synthesis of AMG 133 (HY-164535).
    AMG133 peptide payload TFA
  • HY-P1449
    Boc-Gly-Gly-Phe-Gly-OH 187794-49-6 99.88%
    Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
    Boc-Gly-Gly-Phe-Gly-OH
  • HY-P10069
    Ac-pSar12-OH 2313534-24-4 99.52%
    Ac-pSar12-OH is a water-soluble polymer of the polysarcosine class and can be used as a linker.
    Ac-pSar12-OH
  • HY-P4192
    Fomc-Gly-Gly-Phe-Gly-OH 1817857-75-2 99.66%
    Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit.
    Fomc-Gly-Gly-Phe-Gly-OH
  • HY-136432
    Mc-Gly-Gly-Phe-Gly-PAB-OH 2632342-05-1 98.81%
    Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
    Mc-Gly-Gly-Phe-Gly-PAB-OH
  • HY-P11016
    PLGLAG 726172-45-8 99.63%
    PLGLAG is a peptide that serves as the linker in activatable cell-penetrating peptides (ACPPs) and can be used in cancer research.
    PLGLAG
  • HY-P4166
    Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar 2857963-60-9 99.91%
    Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar is a decapeptide. Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar can be used to preparation of antibody-drug conjugate.
    Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar
  • HY-W142467
    Tetraglycine 637-84-3 98.09%
    Tetraglycine is a oligopeptide composed of four glycine monomers.
    Tetraglycine
  • HY-170534
    Ac-EEVC-OH 2921734-44-1 99.11%
    Ac-EEVC-OH is a ADC Linker that can be used for the synthesis of ADC molecules.
    Ac-EEVC-OH
  • HY-P3438A
    PRRVRLK acetate 98.18%
    PRRVRLK acetate is a peptide linker. PRRVRLK acetate can be used to make fusion protein.
    PRRVRLK acetate
  • HY-P3669
    Gly-Gly-Phe-Gly 200427-88-9 99.22%
    Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates. Gly-Gly-Phe-Gly can be used as an ADC linker to synthesize ADCs, such as Puxitatug samrotecan (AZD 8205) (HY-171689).
    Gly-Gly-Phe-Gly
  • HY-P3497A
    Fmoc-Cys-Asp10 TFA
    Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times.
    Fmoc-Cys-Asp10 TFA
  • HY-P3497
    Fmoc-Cys-Asp10 2407782-70-9
    Fmoc-Cys-Asp10 is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times.
    Fmoc-Cys-Asp10
  • HY-136432A
    Mc-Gly-Gly-Phe-Gly-PAB-OH TFA 2991254-82-9
    Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
    Mc-Gly-Gly-Phe-Gly-PAB-OH TFA
  • HY-P5299
    Fmoc-Gly-Gly-OSu 114726-49-7 98.16%
    Fmoc-Gly-Gly-OSu (Compound 98-6) is a dipeptide that can be used to synthesize ADC linker.
    Fmoc-Gly-Gly-OSu
  • HY-P11229
    GGGGSGGGGS 192805-56-4
    GGGGSGGGGS is a chimeric peptide composed of four peptides. GGGGSGGGGS can efficiently bind to small intestinal submucosa (SIS) membranes. GGGGSGGGGS can be used for research on infectious or inflammatory conditions.
    GGGGSGGGGS
  • HY-W800626
    Boc-PEG6-Val-Cit-PAB-OH 2055024-53-6
    Boc-PEG6-Val-Cit-PAB-OH is an ADC linker that can be used for synthesizing antibody-drug conjugates (ADC). Boc-PEG6-Val-Cit-PAB-OH can be used for cancer research.
    Boc-PEG6-Val-Cit-PAB-OH
  • HY-P10070
    Ac-pSar16-OH
    Ac-pSar16-OH is a polysarcosine which can replace PEG for therapeutic protein conjugation.
    Ac-pSar16-OH
  • HY-P5768A
    2× ST-tag II TFA
    2× ST-tag II TFA is an oligopeptide that can link proteins and dsDNA molecules in an efficient, rapid and specific manner. 2× ST-tag II is a peptide ligand of ST Tactin (STN). 2× ST-tag II TFA specifically binds to ST Tactin. 2× ST-tag II TFA can be used to construct DNA-protein hybrids.
    2× ST-tag II TFA
  • HY-P5768
    2× ST-tag II 2771233-98-6
    2× ST-tag II is an oligopeptide that can link proteins and dsDNA molecules in an efficient, rapid and specific manner. 2× ST-tag II is a peptide ligand of ST Tactin (STN). 2× ST-tag II specifically binds to ST Tactin. 2× ST-tag II can be used to construct DNA-protein hybrids.
    2× ST-tag II