Mc-Gly-Gly-Phe-Gly-PAB-OH
Based on 1 Customer Validation
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity : 98.81%
- CAS No.: 2632342-05-1
- Formula: C32H38N6O8
- Molecular Weight:634.68
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
Cleavable Linker |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2632342-05-1
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Appearance Solid
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Molecular Weight 634.68
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Formula C32H38N6O8
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Color White to yellow
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Synonyms
Mc-GGFG-PAB-OH
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 233.33 mg/mL (367.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5756 mL | 7.8780 mL | 15.7560 mL | 39.3899 mL |
| 5 mM | 0.3151 mL | 1.5756 mL | 3.1512 mL | 7.8780 mL | |
| 10 mM | 0.1576 mL | 0.7878 mL | 1.5756 mL | 3.9390 mL | |
| 15 mM | 0.1050 mL | 0.5252 mL | 1.0504 mL | 2.6260 mL | |
| 20 mM | 0.0788 mL | 0.3939 mL | 0.7878 mL | 1.9695 mL | |
| 25 mM | 0.0630 mL | 0.3151 mL | 0.6302 mL | 1.5756 mL | |
| 30 mM | 0.0525 mL | 0.2626 mL | 0.5252 mL | 1.3130 mL | |
| 40 mM | 0.0394 mL | 0.1969 mL | 0.3939 mL | 0.9847 mL | |
| 50 mM | 0.0315 mL | 0.1576 mL | 0.3151 mL | 0.7878 mL | |
| 60 mM | 0.0263 mL | 0.1313 mL | 0.2626 mL | 0.6565 mL | |
| 80 mM | 0.0197 mL | 0.0985 mL | 0.1969 mL | 0.4924 mL | |
| 100 mM | 0.0158 mL | 0.0788 mL | 0.1576 mL | 0.3939 mL |
Mc-Gly-Gly-Phe-Gly-PAB-OH Related Classifications
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