1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. Fomc-Gly-Gly-Phe-Gly-OH

Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit.

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Fomc-Gly-Gly-Phe-Gly-OH

Fomc-Gly-Gly-Phe-Gly-OH Estructura química

No. CAS : 1817857-75-2

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Descripciòn

Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit[1].

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

558.58

Fòrmula

C30H30N4O7

No. CAS
Appearance

Solid

Color

White to off-white

Sequence

Fomc-Gly-Gly-Phe-Gly

Sequence Shortening

Fomc-GGFG

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad
In Vitro: 

DMSO : 125 mg/mL (223.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7903 mL 8.9513 mL 17.9025 mL
5 mM 0.3581 mL 1.7903 mL 3.5805 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 99.66%

Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7903 mL 8.9513 mL 17.9025 mL 44.7563 mL
5 mM 0.3581 mL 1.7903 mL 3.5805 mL 8.9513 mL
10 mM 0.1790 mL 0.8951 mL 1.7903 mL 4.4756 mL
15 mM 0.1194 mL 0.5968 mL 1.1935 mL 2.9838 mL
20 mM 0.0895 mL 0.4476 mL 0.8951 mL 2.2378 mL
25 mM 0.0716 mL 0.3581 mL 0.7161 mL 1.7903 mL
30 mM 0.0597 mL 0.2984 mL 0.5968 mL 1.4919 mL
40 mM 0.0448 mL 0.2238 mL 0.4476 mL 1.1189 mL
50 mM 0.0358 mL 0.1790 mL 0.3581 mL 0.8951 mL
60 mM 0.0298 mL 0.1492 mL 0.2984 mL 0.7459 mL
80 mM 0.0224 mL 0.1119 mL 0.2238 mL 0.5595 mL
100 mM 0.0179 mL 0.0895 mL 0.1790 mL 0.4476 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Fomc-Gly-Gly-Phe-Gly-OH
Cat. No.:
HY-P4192
Cantidad:
MCE Japan Authorized Agent: