2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Fomc-Gly-Gly-Phe-Gly-OH

Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit.

For research use only. We do not sell to patients.

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Fomc-Gly-Gly-Phe-Gly-OH Chemical Structure

Fomc-Gly-Gly-Phe-Gly-OH Chemical Structure

CAS No. : 1817857-75-2

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Based on 1 publication(s) in Google Scholar

Fomc-Gly-Gly-Phe-Gly-OH Related Antibodies

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Description

Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit[1].

Molecular Weight

558.58

Formula

C30H30N4O7
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Fomc-Gly-Gly-Phe-Gly
Sequence Shortening

Fomc-GGFG
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (223.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7903 mL 8.9513 mL 17.9025 mL
5 mM 0.3581 mL 1.7903 mL 3.5805 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.66%

COA (248 KB) HNMR (314 KB) LCMS (86 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7903 mL 8.9513 mL 17.9025 mL 44.7563 mL
5 mM 0.3581 mL 1.7903 mL 3.5805 mL 8.9513 mL
10 mM 0.1790 mL 0.8951 mL 1.7903 mL 4.4756 mL
15 mM 0.1194 mL 0.5968 mL 1.1935 mL 2.9838 mL
20 mM 0.0895 mL 0.4476 mL 0.8951 mL 2.2378 mL
25 mM 0.0716 mL 0.3581 mL 0.7161 mL 1.7903 mL
30 mM 0.0597 mL 0.2984 mL 0.5968 mL 1.4919 mL
40 mM 0.0448 mL 0.2238 mL 0.4476 mL 1.1189 mL
50 mM 0.0358 mL 0.1790 mL 0.3581 mL 0.8951 mL
60 mM 0.0298 mL 0.1492 mL 0.2984 mL 0.7459 mL
80 mM 0.0224 mL 0.1119 mL 0.2238 mL 0.5595 mL
100 mM 0.0179 mL 0.0895 mL 0.1790 mL 0.4476 mL
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Fomc-Gly-Gly-Phe-Gly-OH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fomc-Gly-Gly-Phe-Gly-OH1817857-75-2ADC LinkerAntibody-drug conjugates linkerdual-drug link assembly unitcancerInhibitorinhibitorinhibit

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