1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. Fmoc-Val-Cit-PAB

Fmoc-Val-Cit-PAB 

Cat. No.: HY-19318 Purity: 97.15%
Handling Instructions

Fmoc-Val-Cit-PAB is a cleavable linker for antibody-drug-conjugation (ADC).

For research use only. We do not sell to patients.

Fmoc-Val-Cit-PAB Chemical Structure

Fmoc-Val-Cit-PAB Chemical Structure

CAS No. : 159858-22-7

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Free Sample (0.5-1 mg)   Apply Now  
250 mg USD 300 In-stock
Estimated Time of Arrival: December 31
500 mg USD 500 In-stock
Estimated Time of Arrival: December 31
1 g USD 850 In-stock
Estimated Time of Arrival: December 31
5 g   Get quote  
10 g   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Fmoc-Val-Cit-PAB:

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Description

Fmoc-Val-Cit-PAB is a cleavable linker for antibody-drug-conjugation (ADC).

IC50 & Target

Cleavable

 

Molecular Weight

601.69

Formula

C₃₃H₃₉N₅O₆

CAS No.

159858-22-7

SMILES

CC(C)[[email protected]@H](C(N[[email protected]@H](CCCNC(N)=O)C(NC1=CC=C(CO)C=C1)=O)=O)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (166.20 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6620 mL 8.3099 mL 16.6199 mL
5 mM 0.3324 mL 1.6620 mL 3.3240 mL
10 mM 0.1662 mL 0.8310 mL 1.6620 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 5 mg/mL (8.31 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 5 mg/mL (8.31 mM); Clear solution

*All of the co-solvents are provided by MCE.
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Fmoc-Val-Cit-PABADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Product Name:
Fmoc-Val-Cit-PAB
Cat. No.:
HY-19318
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