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  3. Tetrazine-Amine monohydrochloride

Tetrazine-Amine monohydrochloride  (Synonyms: (4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine (monohydrochloride); Tetrazine-NH2 monohydrochloride)

製品番号: HY-W053709A 純度: 99.38%
COA 取扱説明書 Technical Support

Tetrazine-Amine monohydrochloride is the monohydrochloride form of Tetrazine-Amine (HY-W053709). Tetrazine-amine is a Tetrazine linker that can be used to covalently label living cells by cycloaddition. Tetrazine-Amine (monohydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

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Tetrazine-Amine monohydrochloride

Tetrazine-Amine monohydrochloride 構造式

CAS 番号 : 1416711-59-5

容量 価格(税別) 在庫状況 数量
>無料サンプル (0.1 - 0.2 mg)   今すぐ申し込む  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 77 在庫あり
Solution
10 mM * 1 mL in DMSO USD 77 在庫あり
Solid
25 mg $70 在庫あり
50 mg $110 在庫あり
100 mg $180 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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製品説明

Tetrazine-Amine monohydrochloride is the monohydrochloride form of Tetrazine-Amine (HY-W053709). Tetrazine-amine is a Tetrazine linker that can be used to covalently label living cells by cycloaddition[1][2]. Tetrazine-Amine (monohydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

体外実験

Click chemistry is used to describe the selective, modular, wide range and high-yield chemical reactions that allow rapid synthesis of new compounds through heteroatom linking (C-X-C). Bertozzi developed click chemistry in a new dimension —Bioorthogonal chemistry. It is defined as a rapid and selective reaction that does not interfere with biological processes under physiological conditions. Common reaction structures of click chemistry, such as Azide, Alkyne, DBCO, BCN, TCO and Tetrazine.?

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

223.67

分子式

C9H10ClN5

CAS 番号
Appearance

Solid

Color

Purple to purplish red

SMILES

NCC1=CC=C(C2=NN=CN=N2)C=C1.Cl

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶剤 & 溶解度
体外: 

H2O : ≥ 100 mg/mL (447.09 mM)

DMSO : 62.5 mg/mL (279.43 mM; ultrasonic and warming and heat to 70°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4709 mL 22.3547 mL 44.7093 mL
5 mM 0.8942 mL 4.4709 mL 8.9419 mL
10 mM 0.4471 mL 2.2355 mL 4.4709 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始)

C1

×
体積 (開始)

V1

=
濃度 (終了)

C2

×
体積 (終了)

V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 99.38%

参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 4.4709 mL 22.3547 mL 44.7093 mL 111.7733 mL
5 mM 0.8942 mL 4.4709 mL 8.9419 mL 22.3547 mL
10 mM 0.4471 mL 2.2355 mL 4.4709 mL 11.1773 mL
15 mM 0.2981 mL 1.4903 mL 2.9806 mL 7.4516 mL
20 mM 0.2235 mL 1.1177 mL 2.2355 mL 5.5887 mL
25 mM 0.1788 mL 0.8942 mL 1.7884 mL 4.4709 mL
30 mM 0.1490 mL 0.7452 mL 1.4903 mL 3.7258 mL
40 mM 0.1118 mL 0.5589 mL 1.1177 mL 2.7943 mL
50 mM 0.0894 mL 0.4471 mL 0.8942 mL 2.2355 mL
60 mM 0.0745 mL 0.3726 mL 0.7452 mL 1.8629 mL
80 mM 0.0559 mL 0.2794 mL 0.5589 mL 1.3972 mL
100 mM 0.0447 mL 0.2235 mL 0.4471 mL 1.1177 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
Tetrazine-Amine monohydrochloride
製品番号:
HY-W053709A
数量:
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