Trifluoroacetyl tripeptide-2

Name: Trifluoroacetyl tripeptide-2
Brand: MedChemExpress
SKU: HY-P5238
Rating: 4.5 (0 reviews)

Cat. No.: HY-P5238 Pureza: 98.71%: Ficha de datos
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Trifluoroacetyl tripeptide-2 is a tripeptide with strong cosmetic activity. Trifluoroacetyl tripeptide-2 can regulate progerin synthesis, promote extracellular matrix synthesis, and improve skin elasticity. Trifluoroacetyl tripeptide-2 has anti-wrinkle and firming effects and can be used as an anti-aging ingredient in cosmetic research.

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Síntesis de péptidos personalizados

Trifluoroacetyl tripeptide-2 Estructura química

No. CAS : 64577-63-5

Tamaño	Stock	Cantidad
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
200 mg	Obtener un presupuesto
500 mg	Obtener un presupuesto

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Actividad biológica
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Referencias
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Descripciòn

In Vitro

Trifluoroacetyl tripeptide-2 (0.1 mg/mL; 24 h; in the form of hydrogel) shows permeability in pig ear skin^[2].
Trifluoroacetyl tripeptide-2 (1 mg; 24-48 h) has no significant effect on the viability of human immortalized keratinocyte HaCaT^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[2]

Cell Line:	HaCaT cells
Concentration:	1 mg
Incubation Time:	24 and 48 h
Result:	Had no significant effect on the cell viability and the cells continue to proliferate after 48 h.

Peso molecular

475.46

Fòrmula

C₂₁H₂₈F₃N₃O₆

No. CAS

64577-63-5

Appearance

Solid

Color

White to off-white

Sequence

{Tfa}-Val-Tyr-Val

Sequence Shortening

{Tfa}-VYV

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

DMSO : ≥ 175 mg/mL (368.06 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1032 mL	10.5161 mL	21.0323 mL
5 mM	0.4206 mL	2.1032 mL	4.2065 mL
10 mM	0.2103 mL	1.0516 mL	2.1032 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureza y Documentación

Purity: 98.71%

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Ficha de datos (274 KB) SDS (252 KB)

COA (249 KB) HNMR (299 KB) LCMS (94 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Beldio Research GmbH, et al. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics 2017, 4(2), 16

[2]. Shariati Pour SR, et al. Delivery of Active Peptides by Self-Healing, Biocompatible and Supramolecular Hydrogels. Molecules. 2023 Mar 10;28(6):2528. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1032 mL	10.5161 mL	21.0323 mL	52.5807 mL
	5 mM	0.4206 mL	2.1032 mL	4.2065 mL	10.5161 mL
	10 mM	0.2103 mL	1.0516 mL	2.1032 mL	5.2581 mL
	15 mM	0.1402 mL	0.7011 mL	1.4022 mL	3.5054 mL
	20 mM	0.1052 mL	0.5258 mL	1.0516 mL	2.6290 mL
	25 mM	0.0841 mL	0.4206 mL	0.8413 mL	2.1032 mL
	30 mM	0.0701 mL	0.3505 mL	0.7011 mL	1.7527 mL
	40 mM	0.0526 mL	0.2629 mL	0.5258 mL	1.3145 mL
	50 mM	0.0421 mL	0.2103 mL	0.4206 mL	1.0516 mL
	60 mM	0.0351 mL	0.1753 mL	0.3505 mL	0.8763 mL
	80 mM	0.0263 mL	0.1315 mL	0.2629 mL	0.6573 mL
	100 mM	0.0210 mL	0.1052 mL	0.2103 mL	0.5258 mL