White mineral oil  (Synonyms: Paraffin oil)

White mineral oil is the highly refined mineral oil, and is composed of saturated aliphatic and alicyclic nonpolar hydrocarbons. White mineral oil is biologically and chemically stable, and doesn’t support pathogenic bacterial growth. White mineral oil can resist moisture, extend, soften, smoothen, and lubricate^[1].

White mineral oil (6-14 days) supports the developmental capacity of bovine oocytes with improved morula- and blastocyst development rate^[3].
White mineral oil (2.5-10 % v/v, 4-10 days) promotes the growth of methylotrophic bacteria by increasing the solubility of methane in the culture medium, thereby enhancing the efficiency of methane transfer from the gas phase to the liquid phase^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

White mineral oil (2-2000 mg/kg, po for 90 days) cause liver granulomas and mesenteric lymph node histiocytosis in Fischer 344 rats models, and the white mineral oil response exhibits great differences among species and strains^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

8042-47-5

Liquid (Density: 0.85 g/cm³)

Colorless to light yellow

[White mineral oil]

Room temperature in continental US; may vary elsewhere.

Store at room temperature 3 years

• [1]. J F Nash, et al. A toxicological review of topical exposure to white mineral oils. Food Chem Toxicol. 1996 Feb;34(2):213-25.  [Content Brief]

  [2]. Miller MJ, et al., Variable responses of species and strains to white mineral oils and paraffin waxes. Regul Toxicol Pharmacol. 1996 Feb;23(1 Pt 1):55-68.  [Content Brief]

  [3]. Tae JC, et al., Sterile filtered paraffin oil supports in vitro developmental competence in bovine embryos comparable to co-culture. J Assist Reprod Genet. 2006 Mar;23(3):121-7.  [Content Brief]

  [4]. Han B, et al., Paraffin oil as a "methane vector" for rapid and high cell density cultivation of Methylosinus trichosporium OB3b. Appl Microbiol Biotechnol. 2009 Jun;83(4):669-77.  [Content Brief]