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  3. 1-Octacosanol

1-Octacosanol is a straight-chain aliphatic 28-carbon fatty alcohol and a major component of the cholesterol-lowering agent Policosanol. 1-Octacosanol exhibits various activities such as anti-fatigue, anti-angiogenic, cholesterol-lowering, and insecticidal effects.

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1-Octacosanol

1-Octacosanol Estructura química

No. CAS : 557-61-9

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Descripciòn

1-Octacosanol is a straight-chain aliphatic 28-carbon fatty alcohol and a major component of the cholesterol-lowering agent Policosanol. 1-Octacosanol exhibits various activities such as anti-fatigue, anti-angiogenic, cholesterol-lowering, and insecticidal effects[1][2][3].

Cellular Effect
Cell Line Type Value Description References
Vero CC50
>100 6
Compound: 8
Cytotoxicity against african green monkey Vero cells after 72 hrs by resazurin dye-based fluorimetric analysis
Cytotoxicity against african green monkey Vero cells after 72 hrs by resazurin dye-based fluorimetric analysis
[PMID: 22348826]
Vero CC50
> 100 6
Compound: 8
Cytotoxicity against african green monkey Vero cells after 72 hrs by resazurin dye-based fluorimetric analysis
Cytotoxicity against african green monkey Vero cells after 72 hrs by resazurin dye-based fluorimetric analysis
[PMID: 22348826]
Vero CC50
> 100 6
Compound: 8
Cytotoxicity against african green monkey Vero cells after 72 hrs by resazurin dye-based fluorimetric analysis
Cytotoxicity against african green monkey Vero cells after 72 hrs by resazurin dye-based fluorimetric analysis
[PMID: 22348826]
In Vivo

1-Octacosanol (80-1000 ppm) has insecticidal activity against Spodoptera frugiperda[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

410.77

Fòrmula

C28H58O

No. CAS
Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCCCCCCCCCCCCCCCCCCO

Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvente y solubilidad
In Vitro: 

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Ethanol : < 1 mg/mL (insoluble)

H2O : < 0.1 mg/mL (insoluble)

*1-Octacosanol is usually formulated as a suspension.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 98.0%

Referencias
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
1-Octacosanol
Cat. No.:
HY-N6811
Cantidad:
MCE Japan Authorized Agent: