1. Metabolic Enzyme/Protease GPCR/G Protein
  2. Endogenous Metabolite Platelet-activating Factor Receptor (PAFR)
  3. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine

1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine  (Synonyms: (Rac)-PAF (C16))

Cat. No.: HY-115702
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1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine ((Rac)-PAF (C16)) is an endogenous inflammatory lipid mediator. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine acts as a high-affinity agonist for PAFR (GPCR), inducing platelet aggregation, vascular permeability, and leukocyte chemotaxis at extremely low concentrations. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine exerts its effects via cell surface receptors to regulate inflammation.

For research use only. We do not sell to patients.

1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine

1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine Chemical Structure

CAS No. : 77286-68-1

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Other Forms of 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine:

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Description

1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine ((Rac)-PAF (C16)) is an endogenous inflammatory lipid mediator. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine acts as a high-affinity agonist for PAFR (GPCR), inducing platelet aggregation, vascular permeability, and leukocyte chemotaxis at extremely low concentrations. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine exerts its effects via cell surface receptors to regulate inflammation[1].

In Vitro

1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine (PAF) (1 pM-1 nM) induces platelet aggregation, dense granule release, and morphological changes in rabbit/human platelets[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

523.69

Formula

C26H54NO7P

CAS No.
SMILES

O=C(OC(COCCCCCCCCCCCCCCCC)COP(=O)([O-])OCC[N+](C)(C)C)C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine
Cat. No.:
HY-115702
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