1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d₁₁

Cat. No.: HY-126356S: Data Sheet Handling Instructions
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1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d₁₁ is the deuterium labeled 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (HY-126356). 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is a major phospholipid in low-density lipoprotein and belongs to the group of 1-acyl phosphatidylcholines. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine does not induce morphological changes in washed human platelets. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine can be used for the research of atherosclerosis and thrombotic diseases.

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1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d<sub>11</sub>

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d₁₁ 화학구조

사이즈		재고
MOQ		Minimum order quantity
50 mg		견적 받기
100 mg		견적 받기
250 mg		견적 받기
Other size		견적 받기

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This product is a controlled substance and not for sale in your territory.

Other Forms of 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d₁₁:

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine In-stock
1-Stearoyl-2-Arachidonoyl-d₈-sn-glycero-3-PC In-stock

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

821.20

화학식

C₄₆H₇₃D₁₁NO₈P

Unlabeled CAS

35418-59-8

SMILES

CCCCCCCCCCCCCCCCCC(OC[C@@H](OC(CCC/C=C\C/C=C\C/C=C\C/C=C\C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)COP(OCC[N+](C)(C)C)([O-])=O)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

용액&용해도

In Vitro:

Ethanol : 30 mg/mL (36.53 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.2177 mL	6.0887 mL	12.1773 mL
5 mM	0.2435 mL	1.2177 mL	2.4355 mL
10 mM	0.1218 mL	0.6089 mL	1.2177 mL

View the Complete Stock Solution Preparation Table

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Ethanol	1 mM	1.2177 mL	6.0887 mL	12.1773 mL	30.4433 mL
	5 mM	0.2435 mL	1.2177 mL	2.4355 mL	6.0887 mL
	10 mM	0.1218 mL	0.6089 mL	1.2177 mL	3.0443 mL
	15 mM	0.0812 mL	0.4059 mL	0.8118 mL	2.0296 mL
	20 mM	0.0609 mL	0.3044 mL	0.6089 mL	1.5222 mL
	25 mM	0.0487 mL	0.2435 mL	0.4871 mL	1.2177 mL
	30 mM	0.0406 mL	0.2030 mL	0.4059 mL	1.0148 mL