1. GPCR/G Protein
  2. Prostaglandin Receptor
  3. 17-Phenyl trinor prostaglandin E2 ethyl amide

17-Phenyl trinor prostaglandin E2 ethyl amide  (Synonyms: 17-Phenyl trinor PGE2 ethyl amide)

Cat. No.: HY-138868
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17-Phenyl trinor prostaglandin E2 ethyl amide (17-Phenyl trinor PGE2 ethyl amide) is a EP1 receptor agonist. 17-Phenyl trinor prostaglandin E2 ethyl amide aggravates renal dysfunction and glomerulosclerosis.

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17-Phenyl trinor prostaglandin E2 ethyl amide

17-Phenyl trinor prostaglandin E2 ethyl amide 화학구조

CAS No. : 1219032-20-8

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제품 설명

17-Phenyl trinor prostaglandin E2 ethyl amide (17-Phenyl trinor PGE2 ethyl amide) is a EP1 receptor agonist. 17-Phenyl trinor prostaglandin E2 ethyl amide aggravates renal dysfunction and glomerulosclerosis[1].

In Vivo

17-Phenyl trinor prostaglandin E2 ethyl amide (0.3 µg/g; i.p.; three times a week for 12 weeks) aggravates renal dysfunction and glomerulosclerosis in five‑sixths nephrectomy renal fibrosis model mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 8-12 weeks, 15-20 g, C57/BL6 male mice (five‑sixths nephrectomy renal fibrosis model)[1]
Dosage: 0.3 µg/g
Administration: I.p.; three times a week for 12 weeks
Result: Increased the plasma blood urea nitrogen (BUN) levels and plasma creatinine (Cr) concentration, increased the extracellular matrix and the area of collagen deposition, upregulated the protein of expression of Col1, GRP78, TRPC1 and PERK in 5/6 Nx mice.
분자량

413.55

화학식

C25H35NO4

CAS No.
SMILES

O[C@@H](CCC1=CC=CC=C1)/C=C/[C@@H]2[C@H](C(C[C@H]2O)=O)C/C=C\CCCC(NCC)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서
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17-Phenyl trinor prostaglandin E2 ethyl amide Related Classifications

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상품명:
17-Phenyl trinor prostaglandin E2 ethyl amide
Cat. No.:
HY-138868
수량:
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