6-Azido-hexylamine

Name: 6-Azido-hexylamine
Brand: MedChemExpress
SKU: HY-138387
Rating: 4.5 (0 reviews)

Cat. No.: HY-138387 Pureté: 98.69%: Fiche technique
COA

SDS
Instruction de manipulation
FAQs
Technical Support

6-Azido-hexylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 6-Azido-hexylamine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

6-Azido-hexylamine Chemical Structure

CAS No. : 349553-73-7

Size	Stock	Quantité
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
250 mg	En stock	Estimated Time of Arrival: December 31
500 mg	En stock	Estimated Time of Arrival: December 31
1 g	En stock	Estimated Time of Arrival: December 31
5 g	En stock	Estimated Time of Arrival: December 31
10 g	Obtenir un devis
50 g	Obtenir un devis

or Bulk Inquiry

* Veuillez sélectionner la quantité avant d'ajouter des articles.

This product is a controlled substance and not for sale in your territory.

Avis client

Based on 1 Customer Validation

Recommandations en vedette

•Related Small Molecules:

•Related Proteins:

Voir tous les produits spécifiques à Isoform ADC Linker:

Voir toutes les isoformes

Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

Activité biologique
Pureté et documentation
Références
Avis client

Description

6-Azido-hexylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1]. 6-Azido-hexylamine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC₅₀ & Target

Cleavable Linker

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Masse moléculaire

142.20

Formule

C₆H₁₄N₄

CAS No.

349553-73-7

Appearance

Liquid

Color

Colorless to light yellow

SMILES

NCCCCCCN=[N+]=[N-]

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Pureté et documentation

Purity: 98.69%

Select Batch:

Fiche technique (262 KB) SDS (466 KB)

COA (240 KB) HNMR (126 KB) GC (236 KB)

Instruction de manipulation (2659 KB)

Références

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. [Content Brief]