2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. 6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole 

Cat. No.: HY-W158948
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6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole is a ORL-1 receptor modulator. 6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole regulates downstream pathways associated with nociception, cognition and physiological processes. 6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole is used in the research of central nervous system diseases and pain-related disorders including anxiety, depression, Alzheimer's disease and attention deficit disorder.

For research use only. We do not sell to patients.

6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Chemical Structure

CAS No. : 180161-14-2

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6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Related Antibodies

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μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

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Description

6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole is a ORL-1 receptor modulator. 6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole regulates downstream pathways associated with nociception, cognition and physiological processes. 6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole is used in the research of central nervous system diseases and pain-related disorders including anxiety, depression, Alzheimer's disease and attention deficit disorder[1].

IC50 & Target[1]

human μ-opioid receptor

 

human κ-opioid receptor (hKOR)

 

δ Opioid Receptor/DOR

 

In Vitro

6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (Compound 48) exhibits no significant binding activity to μ-opioid receptor (IC50 > 5000 nM), κ-opioid receptor (IC50 > 5000 nM) and δ-opioid receptor (IC50 > 5000 nM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Related Antibodies
Molecular Weight

216.26

Formula

C13H13FN2
CAS No.
SMILES

FC=1C=CC2=C(C1)NC=C2C3=CCNCC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole180161-14-2Opioid Receptor2D4 cell membranes1D4 cell membranesHEK293 cellsORL-1 (nociceptin) receptorcognitionnociceptiondelta opioid receptorsAlzheimer's diseaseneuropathic painmu opioid receptorsInhibitorinhibitorinhibit

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