2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Clenbuterol hydrochloride

Clenbuterol hydrochloride  (Synonyms: NAB-365 hydrochloride)

Cat. No.: HY-B1614 Purity: 99.94%
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Handling Instructions Technical Support

Clenbuterol (NAB-365) hydrochloride, a selective β2-adrenergic agonist, enhances skeletal muscle strength and hypertrophy. Clenbuterol hydrochloride induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage.

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Clenbuterol hydrochloride

Clenbuterol hydrochloride 화학구조

CAS No. : 21898-19-1

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

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고객리뷰

Based on 6 publication(s) in Google Scholar

Other Forms of Clenbuterol hydrochloride:

Clenbuterol hydrochloride Related Antibodies

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  • Biological Activity

  • Protocol

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Clenbuterol (NAB-365) hydrochloride, a selective β2-adrenergic agonist, enhances skeletal muscle strength and hypertrophy. Clenbuterol hydrochloride induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage[1][2][3].

In Vitro

Clenbuterol increases lipolysis in rat primary adipocytes compared with control. Free glycerol release into the culture medium is 158% and 190% of control values in cultures containing 0.1, or 1 μM Clenbuterol, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clenbuterol hydrochloride Related Antibodies
In Vivo

Clenbuterol (0.01-0.5 mg/kg; i.p.; male Long-Evans rats) hydrochloride reduces the cortical infarct volume in Long-Evans rats as measured 7 days after permanent occlusion of the middle cerebral artery[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
분자량

313.65

화학식

C12H19Cl3N2O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(CNC(C)(C)C)C1=CC(Cl)=C(N)C(Cl)=C1.[H]Cl
Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도
In Vitro: 

DMSO : 83.33 mg/mL (265.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1883 mL 15.9413 mL 31.8827 mL
5 mM 0.6377 mL 3.1883 mL 6.3765 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서

Purity: 99.98%

SDS (480 KB)

COA (248 KB) HNMR (272 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References
Cell Assay 
[1]

MTS assay is performed to determine the number of viable cells in culture. Cells are treated with 0 (vehicle only), 0.1, or 1 μM Clenbuterol for 6, 12, 24, or 48 h. The absorbance is measured at 490 nm in a plate reader determine the formazan concentration, which is proportional to the number of living cells in culture[1].

MCE 는 독립적으로 이러한 방법들의 정확성을 확인하지 않았습니다. 참고용으로만 봐주십시오.
Animal Administration
[2]

Rats:
Rats are randomly divided into two treatment groups. The control group is provided with standard chow and water ad libitum for 3 weeks, while the Clenbuterol group is provided with standard chow and treated for 3 weeks with Clenbuterol administered via the drinking water (30 mg Clenbuterol/L). Body weight and the amount of water consumed are recorded twice each week. After 3 wk, the animals are anesthetized and hindlimb muscles are excised[2].

MCE 는 독립적으로 이러한 방법들의 정확성을 확인하지 않았습니다. 참고용으로만 봐주십시오.
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1883 mL 15.9413 mL 31.8827 mL 79.7067 mL
5 mM 0.6377 mL 3.1883 mL 6.3765 mL 15.9413 mL
10 mM 0.3188 mL 1.5941 mL 3.1883 mL 7.9707 mL
15 mM 0.2126 mL 1.0628 mL 2.1255 mL 5.3138 mL
20 mM 0.1594 mL 0.7971 mL 1.5941 mL 3.9853 mL
25 mM 0.1275 mL 0.6377 mL 1.2753 mL 3.1883 mL
30 mM 0.1063 mL 0.5314 mL 1.0628 mL 2.6569 mL
40 mM 0.0797 mL 0.3985 mL 0.7971 mL 1.9927 mL
50 mM 0.0638 mL 0.3188 mL 0.6377 mL 1.5941 mL
60 mM 0.0531 mL 0.2657 mL 0.5314 mL 1.3284 mL
80 mM 0.0399 mL 0.1993 mL 0.3985 mL 0.9963 mL
100 mM 0.0319 mL 0.1594 mL 0.3188 mL 0.7971 mL
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Clenbuterol hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Clenbuterol21898-19-1NAB-365NAB365NAB 365Adrenergic ReceptorBeta ReceptorastrocytesischemicdamageskeletalmusclestrengthhypertrophyInhibitorinhibitorinhibit

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상품명:
Clenbuterol hydrochloride
Cat. No.:
HY-B1614
수량:
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