2. Anti-infection
  3. Bacterial
  4. MBX-4132

MBX-4132, a member of a chemical class called oxadiazoles that inhibit trans translation by binding to the bacterial ribosome.

For research use only. We do not sell to patients.

MBX-4132 Chemical Structure

MBX-4132 Chemical Structure

CAS No. : 2286411-30-9

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 198 In-stock
Solution
10 mM * 1 mL in DMSO USD 198 In-stock
Solid
1 mg USD 75 In-stock
5 mg USD 180 In-stock
10 mg USD 280 In-stock
25 mg USD 560 In-stock
50 mg USD 900 In-stock
100 mg   Get quote  
200 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

MBX-4132 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE MBX-4132

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

MBX-4132, a member of a chemical class called oxadiazoles that inhibit trans translation by binding to the bacterial ribosome.

In Vitro

MBX-4132, which interferes with protein synthesis by blocking trans translation, has several characteristics that could make it a match for Neisseria gonorrhoeae (N. gonorrhoeae)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MBX-4132 Related Antibodies
Molecular Weight

338.34

Formula

C18H15FN4O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1=NN=C(C2=CC=C(F)C=C2)O1)N3CCC4=CC=CC=C4C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (73.89 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9556 mL 14.7780 mL 29.5561 mL
5 mM 0.5911 mL 2.9556 mL 5.9112 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.22%

COA (246 KB) RP-HPLC (174 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9556 mL 14.7780 mL 29.5561 mL 73.8902 mL
5 mM 0.5911 mL 2.9556 mL 5.9112 mL 14.7780 mL
10 mM 0.2956 mL 1.4778 mL 2.9556 mL 7.3890 mL
15 mM 0.1970 mL 0.9852 mL 1.9704 mL 4.9260 mL
20 mM 0.1478 mL 0.7389 mL 1.4778 mL 3.6945 mL
25 mM 0.1182 mL 0.5911 mL 1.1822 mL 2.9556 mL
30 mM 0.0985 mL 0.4926 mL 0.9852 mL 2.4630 mL
40 mM 0.0739 mL 0.3695 mL 0.7389 mL 1.8473 mL
50 mM 0.0591 mL 0.2956 mL 0.5911 mL 1.4778 mL
60 mM 0.0493 mL 0.2463 mL 0.4926 mL 1.2315 mL
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MBX-4132 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MBX-41322286411-30-9MBX4132MBX 4132BacterialInhibitorinhibitorinhibit

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