MBX-4132
Based on 2 publication(s) in Google Scholar
MBX-4132, a member of a chemical class called oxadiazoles that inhibit trans translation by binding to the bacterial ribosome.
For research use only. We do not sell to patients.
- Purity: 99.19%
- CAS No.: 2286411-30-9
- Formula: C18H15FN4O2
- Molecular Weight:338.34
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) MBX-4132
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Biological Activity
MBX-4132, which interferes with protein synthesis by blocking trans translation, has several characteristics that could make it a match for Neisseria gonorrhoeae (N. gonorrhoeae)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2286411-30-9
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Appearance Solid
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Molecular Weight 338.34
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Formula C18H15FN4O2
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Color White to off-white
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SMILES
O=C(NC1=NN=C(C2=CC=C(F)C=C2)O1)N3CCC4=CC=CC=C4C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (2)
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Journal Impact Factor
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Most Recent
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mBio
Tag-Dependent Substrate Selection of ClpX Underlies Secondary Differentiation of Chlamydia trachomatis. [Abstract]2022 Oct 26;13(5):e0185822. PMID: 36154190 -
Solvent & Solubility
DMSO : 25 mg/mL (73.89 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9556 mL | 14.7780 mL | 29.5561 mL | 73.8902 mL |
| 5 mM | 0.5911 mL | 2.9556 mL | 5.9112 mL | 14.7780 mL | |
| 10 mM | 0.2956 mL | 1.4778 mL | 2.9556 mL | 7.3890 mL | |
| 15 mM | 0.1970 mL | 0.9852 mL | 1.9704 mL | 4.9260 mL | |
| 20 mM | 0.1478 mL | 0.7389 mL | 1.4778 mL | 3.6945 mL | |
| 25 mM | 0.1182 mL | 0.5911 mL | 1.1822 mL | 2.9556 mL | |
| 30 mM | 0.0985 mL | 0.4926 mL | 0.9852 mL | 2.4630 mL | |
| 40 mM | 0.0739 mL | 0.3695 mL | 0.7389 mL | 1.8473 mL | |
| 50 mM | 0.0591 mL | 0.2956 mL | 0.5911 mL | 1.4778 mL | |
| 60 mM | 0.0493 mL | 0.2463 mL | 0.4926 mL | 1.2315 mL |
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