Infection

WIN 54954 is an orally active and broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections.

Di(zanamivir-amide(N-Me)-PEG1)-N-PEG4-alkyne a chemical conjugate containing two Zanamivir (HY-13210) units linked via PEG chains to an alkyne functional group. Di(zanamivir-amide(N-Me)-PEG1)-N-PEG4-alkyne has a molecular weight of 1150.19 and is utilized in antiviral and click-chemistry research.

Dermaseptin TFA, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration.

5'-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.

Cinnamon bark oil, from Cinnamonum zeylanicum Blume is a antifungal agent against fungi causing respiratory tract mycoses.

Antifungal agent 49 (Example 112) is an antifungal agent. Antifungal agent 49 is active against Cryptococcus neoformans with a MIC value of 49 μM.

Crenatoside is a phenylethanol glycoside compound that can be isolated from the ethyl acetate of the tree extract of T. stans var. stans with EC₅₀ value of 34.78 μM. Crenatoside has anti-Zika virus activity.

Cinnamycin (Ro 09-0198) is a tetracyclic peptide antibiotic that binds specifically to phosphatidylethanolamine (PE) .

(+)-Neomenthol is a potent miticide. (+)-Neomenthol shows acaricidal activitie with LD₅₀ values of 0.32, 0.256 µg/mL for Dermatophagoides farinae and Dermatophagoides pteronyssinus, respectively.

8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.

(1R)-Tenofovir amibufenamide ((1R)-HS-10234) is the isomer of Tenofovir amibufenamide, is an orally active antiviral agent. (1R)-Tenofovir amibufenamide ((1R)-HS-10234) is a HIV infection inhibitor and HBV infection inhibitor. (1R)-Tenofovir amibufenamide ((1R)-HS-10234) can be used for HIV infections, hepatitis B research.

Dihydroartemisinic acid (Dihydroqinghao acid) is a biosynthetic precursor to the antimalarial agent Artemisinin (HY-B0094).

Biotin-YVAD-FMK is an inhibitor for vacuolar processing enzyme (VPE), with a 64% inhibition at 5 μM. Biotin-YVAD-FMK is an irreversible substrate for caspase 1.

Norbornane is a component of the essential oil extracted from the rhizomes of Cyperus rotundus from Morocco. Active derivatives of Norbornane are fused heterocyclic compounds with in vitro anti-tumor and anti-Trypanosoma brucei activities. Norbornane and its derivatives can be used in research related to cancers such as leukemia and African trypanosomiasis.

Mitotic kinesin-IN-2 (Page 135, fifteenth) hydrochloride is a Mitotic kinesin inhibitor. Mitotic kinesin-IN-2 hydrochloride inhibits cell proliferation by suppressing mitosis. Mitotic kinesin-IN-2 hydrochloride can be used for cancer, cardiac hypertrophy, immune and inflammatory disorders, fungal infections research.

Golgicide A-2 (GCA-2), a Golgicide A (GCA) derivative, is the most active enantiomer of GCA. Golgicide A-2 displays high selectivity and efficiency in killing An. stephensi larvae and can be used for the research of dengue virus related diseases.

Chlorotris(triphenylphosphine)copper (CuCl(TPP)₃) is a DNA-targeted metal complex. Chlorotris(triphenylphosphine)copper involves non-covalent interactions (such as groove binding mode) through the copper(I) center to affect DNA function, showing inhibitory activity against bacteria, fungi, and tumor cells. Chlorotris(triphenylphosphine)copper is promising for research of antibacterial, antitumor, and antioxidant agents.

5'-O-DMT-3'-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.

Cytarabine-d₂ is the deuterium labeled Cytarabine. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC₅₀ of 16 nM. Cytarabine has antiviral effects against HSV.

Enzaplatovir (BTA-C585) is an orally bioavailable Inhibitor for respiratory syncytial virus (RSV) infection.