Antibiofilm agent-1
Based on 1 publication(s) in Google Scholar
Antibiofilm agent-1 is an antibacterial agent that inhibits growth of Gram-positive pathogens (WO2017011725A1; compound 17).
For research use only. We do not sell to patients.
- CAS No.: 2001602-10-2
- Formula: C11H5Br2Cl2NO2
- Molecular Weight:413.88
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) Antibiofilm agent-1
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
>41.4 μM
Compound: 5
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Cytotoxicity against human HeLa cells assessed as decrease in cell viability measured after 24 hrs by MTS assay
Cytotoxicity against human HeLa cells assessed as decrease in cell viability measured after 24 hrs by MTS assay
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[PMID: 27565555] |
Chemical Information
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CAS No. 2001602-10-2
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Appearance Solid
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Molecular Weight 413.88
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Formula C11H5Br2Cl2NO2
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Color Light yellow to yellow
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SMILES
O=C(C1=C(O)C(Cl)=CC(Cl)=C1)C2=CC(Br)=C(N2)Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Anal Chem
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing. [Abstract]2025 Jun 3;97(21):11099-11109. PMID: 40401576
Solvent & Solubility
DMSO : 100 mg/mL (241.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4162 mL | 12.0808 mL | 24.1616 mL | 60.4040 mL |
| 5 mM | 0.4832 mL | 2.4162 mL | 4.8323 mL | 12.0808 mL | |
| 10 mM | 0.2416 mL | 1.2081 mL | 2.4162 mL | 6.0404 mL | |
| 15 mM | 0.1611 mL | 0.8054 mL | 1.6108 mL | 4.0269 mL | |
| 20 mM | 0.1208 mL | 0.6040 mL | 1.2081 mL | 3.0202 mL | |
| 25 mM | 0.0966 mL | 0.4832 mL | 0.9665 mL | 2.4162 mL | |
| 30 mM | 0.0805 mL | 0.4027 mL | 0.8054 mL | 2.0135 mL | |
| 40 mM | 0.0604 mL | 0.3020 mL | 0.6040 mL | 1.5101 mL | |
| 50 mM | 0.0483 mL | 0.2416 mL | 0.4832 mL | 1.2081 mL | |
| 60 mM | 0.0403 mL | 0.2013 mL | 0.4027 mL | 1.0067 mL | |
| 80 mM | 0.0302 mL | 0.1510 mL | 0.3020 mL | 0.7550 mL | |
| 100 mM | 0.0242 mL | 0.1208 mL | 0.2416 mL | 0.6040 mL |