2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-D3391
    RMR-Tre 98%
    RMR-Tre is a fluorescent probe targeting the mycobacterial acyltransferase Ag85. Under the catalysis of Ag85, RMR-Tre undergoes 6-position mycoloylation and anchors to the mycobacterial membrane, while achieving fluorescence activation by inhibiting the intramolecular twisted charge transfer state transition. RMR-Tre can distinguish live mycobacteria from dead ones through metabolism-driven labeling, enabling rapid, wash-free, low-background detection of viable bacteria. RMR-Tre reports the drug resistance of Mycobacterium tuberculosis via the trehalose catalytic shift activity readout associated with TreS. In addition, RMR-Tre can be combined with flow cytometry or high-content imaging techniques to visualize and quantitatively analyze the metabolic heterogeneity of Mycobacterium tuberculosis related to persistence and drug resistance. RMR-Tre is widely used in tuberculosis-related research.
    RMR-Tre
  • HY-I0516
    PSI 352707 1233335-78-8 98%
    PSI 352707 (GS-566500) is a sofosbuvir metabolite with activity similar to other antiviral compounds. PSI 352707 showed good safety and tolerability in inhibiting chronic hepatitis C virus infection.
    PSI 352707
  • HY-N0080
    Ulopterol 28095-18-3 98%
    Ulopterol is a coumarin isolated from the leaves of Toddalia asiatica (L.) Lam with potent antibacterial and antifungal activities.
    Ulopterol
  • HY-N0199
    Albaspidin AA 3570-40-9 98%
    Albaspidin AA displays strong antibacterial activity against the vegetative form of Paenibacillus larvae (P. larvae) (MIC=220 μM).
    Albaspidin AA
  • HY-N0312
    Rhein-8-glucoside calcium 113443-70-2 98%
    Rhein-8-glucoside calcium, an anthraquinone compound, is isolated from the EtOH extract of the roots of Saussurea lappa. Rhein-8-glucoside calcium is an hPTP1B inhibitor, with an IC50 of 11.5 μM. Rhein-8-glucoside calcium has antibacterial effects.
    Rhein-8-glucoside calcium
  • HY-N0531
    Filixic acid ABA 38226-84-5 98%
    Filixic acid ABA is a molluscicidal agent against B. peregrina adult snails, with an LD50 of 8.40 ppm. Filixic acid ABA shows 100% mortality of B. peregrina at 15 ppm.
    Filixic acid ABA
  • HY-N0954
    (+)-Pinoresinol diacetate 32971-25-8 98%
    (+)-Pinoresinol diacetate is an antifungal agent that can be isolated from Sambucus williamsii.
    (+)-Pinoresinol diacetate
  • HY-N0957
    (±)-Pinoresinol 4263-88-1 98%
    (±)-Pinoresinol is a potent antifungal agent. (±)-Pinoresinol shows antifungal activity.
    (±)-Pinoresinol
  • HY-N0987
    1,4,6-Trihydroxy-5-methoxy-7-prenylxanthone 160623-47-2 98%
    1,4, 6-trihydroxy-5-methoxy-7-prenylxanthone is an antimicrobial agent that can be isolated from the genus garcinia. 1,4, 6-trihydroxy-5-methoxy-7-prenylxanthone inhibits S. aureus and B. cereus with MIC values of 128 μg/mL and 200 μg/mL, respectively.
    1,4,6-Trihydroxy-5-methoxy-7-prenylxanthone
  • HY-N1034
    12-Oxocalanolide A 161753-49-7 98%
    12-Oxocalanolide A (compound 6) is a potent inhibitor of reverse transcriptase from human immunodeficiency virus type 1 (HIV-1) with an IC50 and EC50 of 2.8 and 12 μM, respectively. 12-Oxocalanolide A is the analogue of Calanolide.
    12-Oxocalanolide A
  • HY-N1075
    Walsuronoid B 942582-15-2 98%
    Walsuronoid B is a limonoid can be isolated from Walsura robusta and has weak antimalarial activity.
    Walsuronoid B
  • HY-N1091
    Vibsanin C 74690-89-4 98%
    Vibsanin C is a subtype of vibsanin-type diterpenoids with cytotoxic and antibacterial activities.
    Vibsanin C
  • HY-N1111
    Uncaric acid 123135-05-7 98%
    Uncaric acid (6β,19α-Dihydroxyursolic acid) (compound 6) is a triterpene that can be found in Eriobotrya japonica. Uncaric acid shows anti HIV-1, HRV 1B, SNV activity.
    Uncaric acid
  • HY-N1116
    Tsugafolin 66568-97-6 98%
    Tsugafolin (compound 4) is a dehydroflavone with weak anti-HIV activity (IC50=118 μM) and devoid cytotoxicity (<150 μM). Tsugafolin can be isolated from Vitex leptobotrys.
    Tsugafolin
  • HY-N1130
    Trianthenol 333361-85-6 98%
    Trianthenol is a tetraterpenoid antifungal agent that can be extracted from the whole plant of Trianthema portulacastrum (a plant of the genus Trianthema in the Aizoaceae family).
    Trianthenol
  • HY-N1133
    trans-Methylisoeugenol 6379-72-2 99.59%
    trans-Methylisoeugenol is an insect chemosterilant isolated from Acorus calamus L.
    trans-Methylisoeugenol
  • HY-N1160
    Tetrahydroxysqualene 1043629-23-7 98%
    Tetrahydroxysqualene is a triterpene, possessing antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 10.0 μg/mL. Tetrahydroxysqualene can be isolated from the methanolic extracts of Rhus taitensis Guill.
    Tetrahydroxysqualene
  • HY-N1162
    Tetrahydroamentoflavone 48236-96-0 98%
    Tetrahydroamentoflavone (Amentoflavanone) is a potent xanthine oxidase (XO) inhibitor. Tetrahydroamentoflavone has inhibitory activity for XO with IC50 and Ki values of 92 nM and 0.982 μM, respectively. Tetrahydroamentoflavone can be used for the research of inflammatory disorders and gout.
    Tetrahydroamentoflavone
  • HY-N1219
    Stephanine 517-63-5 98%
    Stephanine ((-)-Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer.
    Stephanine
  • HY-N1289
    Sequosempervirin B 864719-17-5 98%
    Sequosempervirin B, a norlignan isolated from the branches and leaves of Sequoia sempervirens, has antifungal properties. Sequosempervirin B has an inhibitory effect on cyclic AMP phosphodiesterase.
    Sequosempervirin B
Cat. No. Product Name / Synonyms Application Reactivity