Tetrahydroamentoflavone (Synonyms: Amentoflavanone)

Cat. No.: HY-N1162: FAQs
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Tetrahydroamentoflavone (Amentoflavanone) is a potent xanthine oxidase (XO) inhibitor. Tetrahydroamentoflavone has inhibitory activity for XO with IC₅₀ and K_i values of 92 nM and 0.982 μM, respectively. Tetrahydroamentoflavone can be used for the research of inflammatory disorders and gout.

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Tetrahydroamentoflavone Chemical Structure

CAS No. : 48236-96-0

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Description	Tetrahydroamentoflavone (Amentoflavanone) is a potent xanthine oxidase (XO) inhibitor. Tetrahydroamentoflavone has inhibitory activity for XO with IC₅₀ and K_i values of 92 nM and 0.982 μM, respectively. Tetrahydroamentoflavone can be used for the research of inflammatory disorders and gout^[1].
IC₅₀ & Target	IC50: 92 nM (XO)^[1]. Ki: 0.982 μM (XO)^[1].
In Vitro	Tetrahydroamentoflavone has inhibitory activity for XO with IC₅₀ and K_i values of 92 nM and 0.982 μM, respectively^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Tetrahydroamentoflavone Related Antibodies
Molecular Weight	542.49
Formula	C₃₀H₂₂O₁₀
CAS No.	48236-96-0
SMILES	OC1=CC(O)=C(C(C[C@@H](C2=CC=C(C=C2)O)O3)=O)C3=C1C4=CC([C@H]5OC6=CC(O)=CC(O)=C6C(C5)=O)=CC=C4O
Structure Classification	Flavonoids Biflavones
Initial Source	Plants Anacardiaceae Semecarpus anacardium L.f.
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Ranjith Arimboor, et al. Tetrahydroamentoflavone (THA) from Semecarpus anacardium as a potent inhibitor of xanthine oxidase. J Ethnopharmacol. 2011 Feb 16;133(3):1117-20. [Content Brief]

Tetrahydroamentoflavone Related Classifications

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tetrahydroamentoflavone48236-96-0AmentoflavanoneXanthine OxidaseXOxanthine oxidase (XO)inflammatory disordersgoutSemecarpus anacardiumInhibitorinhibitorinhibit

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Tetrahydroamentoflavone (Synonyms: Amentoflavanone)

Tetrahydroamentoflavone Related Antibodies

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