2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N12023
    Deacetylnomilin 3264-90-2 98%
    Deacetylnomilin can be isolated from Citrus reticulata and has antibacterial and antifungal activity. Deacetylnomilin is a potent inhibitor of cell proliferation with an IC50 value of 0.005 ug/mL against estrogen receptor-positive (ER+) cells.
    Deacetylnomilin
  • HY-N12036
    Dihydroobionin B 98%
    Dihydroobionin B is a potent
    Dihydroobionin B
  • HY-N12047
    Schineolignin C 1352185-28-4 98%
    Schineolignin C is a Lignan that can be isolated from the fruit of schisandra chinensis. schisandra chinensis has antihepatitis, antitumor, and anti-HIV-1 activities.
    Schineolignin C
  • HY-N12096
    Galbinic acid 56691-88-4 98%
    Galbinic acid (α-Acetylsalazinic acid), a lichen acid, shows antibacterial activities against the Gram-positive bacteria B. cereus, B. subtilis, and S. aureus (MICs=62.5, 62.5, 250 μg/ml, respectively). Galbinic acid inhibits the Gram-negative bacterium E. coli (MIC=125 μg/ml).
    Galbinic acid
  • HY-N12102
    Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside 1252572-36-3 98%
    Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside (compound 1) is a lignan with anti-HBC activity. Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside targets HBV surface antigen with IC50s of 0.58 mM (HBsAg) and >2.4 mM (HBeAg). Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside can be isolated from star anise.
    Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside
  • HY-N12104
    Trichodimerol 145174-90-9 98%
    Trichodimerol (BMS-182123) is a TNF-α promoter inhibitor that inhibits the activity of lipopolysaccharide-induced cytokine secretion. Trichodimerol inhibits lipopolysaccharide-induced TNF-α promoter activity, reduces steady-state TNF-α mRNA expression, and does not alter the stability of TNF-α mRNA. Trichodimerol inhibits lipopolysaccharide-induced TNF-α secretion in murine and human immune cells. Trichodimerol reduces lipopolysaccharide-induced IL-1β secretion by 25%-50% in vitro. Trichodimerol does not alter total protein synthesis or constitutive lysozyme secretion at effective concentrations. Trichodimerol can be used for the research of septic shock.
    Trichodimerol
  • HY-N12106
    Neosartoricin 1421941-29-8
    Neosartoricin (Fumicycline) (Compound 3), a prenylated anthracenone, is a microbial secondary metabolite. Neosartoricin can be isolated from Aspergillus fumigatus and Neosartorya fischeri. Neosartoricin has immunosuppressive activity, and significantly inhibits T-cell proliferative activity with an IC50 of 3 μM. Neosartoricin may be beneficial to fungal defense, facilitating infection through suppressing the host adaptive immunity without involvement of primary virulence.
    Neosartoricin
  • HY-N12108
    Forphenicine 57784-96-0 98%
    Forphenicine is a bacterial metabolite that is found in S. fulvoviridis and an inhibitor of alkaline phosphatase. Forphenicine inhibits the growth of HL-60 leukemia cells at 10 µM. Forphenicine also increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE).
    Forphenicine
  • HY-N12113
    9-(Z)-Pentacosene 51865-00-0 98%
    9-(Z)-Pentacosene is a olefin that can be isolated from Fannia canicularis. 9-(Z)-Pentacosene has anti-insect activity.
    9-(Z)-Pentacosene
  • HY-N12121
    Piperundecalidine 88660-11-1 98%
    Piperundecalidine is an amide alkaloids that can be purified from Piper longum L. Piperundecalidine shows various biological properties, such as anti-inammatory, analgesic, anti-amoebic, anti-depressant, hepatoprotective,etc..
    Piperundecalidine
  • HY-N12145
    Streptimidone 738-72-7 98%
    Streptimidone (Ao58A) is a bacterial metabolite found in Streptomyces. Streptimidone has antitumor activity.
    Streptimidone
  • HY-N12146
    Spinosyn D 17-pseudoaglycone 131929-55-0 98%
    Spinosyn D 17-pseudoaglycone is a hydrolysis product of the minor insecticide component Spinosyn D (HY-125326).
    Spinosyn D 17-pseudoaglycone
  • HY-N12194
    Cytochalasin O 108050-26-6 98%
    Cytochalasin O (compound 13) is a secondary metabolite of the phytopathogenic fungus P. sp. CIB-109.
    Cytochalasin O
  • HY-N12195
    Cytochalasin R 121964-47-4 98%
    Cytochalasin R (compound 17) is a cytochalasin analogue that can be isolated from the endophytic fungus Phomopsis sp. xz-18. Cytochalasin R shows potential antifungal activity.
    Cytochalasin R
  • HY-N12196
    Terretonin 71911-90-5 98%
    Terretonin is a fungal terpenoid isolated from Aspergillus terreus. The complete biosynthetic pathway of terretonin includes: cytochrome P450 Trt6 catalyzes the oxidation of terrenoid to obtain an unstable intermediate; then it is catalyzed by isomerase Trt14 and processed by non-heme iron-dependent dioxygenase Trt7 to complete the biosynthesis of terretonin.
    Terretonin
  • HY-N12201
    Funiculosin 11055-06-4 98%
    Funiculosin is a neutral lipophilic antibiotic that inhibits DNA and RNA viruses. Funiculosin also has antifungal activity. Funiculosin inhibits infections caused by pathogenic fungi in primary chicken embryo fibroblasts.
    Funiculosin
  • HY-N12228
    Phenelfamycin E 114451-31-9 98%
    Phenelfamycin E is an elfamycin-type antibiotic and is active against Gram-positive anaerobes, including Clostridium difficile. Phenelfamycin E can be used for anti-bacteria research.
    Phenelfamycin E
  • HY-N12229
    Penipurdin A 1821668-16-9 98%
    Penipurdin A (Compound 1), an anthraquinone, is a microbial secondary metabolite. Penipurdin A can be isolated from the soil fungus Penicillium purpurogenum SC0070. Penipurdin A has no significant cytotoxicity against cancer cells, such as A549, HepG2 and Hela cells. Penipurdin A has antibacterial activity against Enterococcus faecalis and Staphylococcus aureus.
    Penipurdin A
  • HY-N12230
    Penicolinate B 1418291-70-9
    Penicolinate B is a picolinic acid derivative that can be isolated from Penicillium sp. Penicolinate B exhibits antimalarial activity (IC50: 1.40 μg/mL), antitubercular activity (MIC: 25.0 μg/mL), activity against Bacillus cereus (IC50: 25.0 μg/mL), and activity against Candida albicans (IC50: 1.45 μg/mL). Penicolinate B also has certain cytotoxicity against cancer cells such as MCF-7, KB, and NCI-H187. Penicolinate B can be used in research on malaria, tuberculosis, bacterial/fungal infections and tumors.
    Penicolinate B
  • HY-N12231
    Carbazomycin B 75139-38-7 98%
    Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC50 Of 1.5 µMsup>[2]sup>[3]sup>[4].
    Carbazomycin B
Cat. No. Product Name / Synonyms Application Reactivity