2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P1063A
    LF11 TFA 98%
    LF11 TFA is a peptide with antibacterial activity.
    LF11 TFA
  • HY-P10653
    C5A 811418-15-2 98%
    C5A is a microbicidal peptide, anti-hepatitis C virus (HCV), and anti-HIV agent. C5A disrupts the membrane integrity of the HIV virion as well as the integrity of the conical capsid core that surrounds the viral genome. C5A inhibits in vitro infectivity of a broad range of primary HIV isolates in various primary target cells. C5A protects mice against vaginal and rectal HIV challenges.
    C5A
  • HY-P1065A
    Apelin-36(rat, mouse) TFA 98%
    Apelin-36(rat, mouse) TFA is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-36(rat, mouse) TFA binds to APJ receptors with an IC50 of 5.4 nM, and potently inhibits cAMP production with an EC50 of 0.52 nM. Apelin-36(rat, mouse) TFA blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.
    Apelin-36(rat, mouse) TFA
  • HY-P10662
    HLA-B*0801-binding EBV peptide 139143-28-5 98%
    HLA-B*0801-binding EBV peptide is an Epstein-Barr virus (EBV) epitope FLRGRAYGL. HLA-B*0801-binding EBV peptide can bind to the HLA-B*0801 molecule. HLA-B*0801-binding EBV peptide can be presented to CD8+ T cells through HLA-B*0801 to activate a specific immune response.
    HLA-B*0801-binding EBV peptide
  • HY-P10663
    EBV EBNA3A (379-387) 160790-25-0 98%
    EBV EBNA3A (379-387) is an antigenic epitope that may elicit the latent-specific CD8+ T cell response in HLA-B*07:02+ individuals.
    EBV EBNA3A (379-387)
  • HY-P1066A
    Apelin-17(human, bovine) TFA 98%
    Apelin-17(human, bovine) TFA is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-17(human, bovine) TFA binds to human APJ receptors expressed in HEK 293 cells (pIC50=9.02). Apelin-17(human, bovine) TFA inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ.
    Apelin-17(human, bovine) TFA
  • HY-P10681
    Crabrolin 93207-22-8 98%
    Crabrolin is a tridecapeptide that can be extracted from the venom of the European hornet (Vespa crabro). Crabrolin shows MIC/MBC of 2/2, 16/64, 4/8 μM, for S. aureus (NCTC 10788), MRSA (NCTC 12493) and E. faecium (NTCC 12697), respectively.
    Crabrolin
  • HY-P10682
    PuroA 639459-67-9 98%
    PuroA is a tryptophan-rich domain of Puroindoline a that exerts antibacterial activity through interaction with bacterial membranes.
    PuroA
  • HY-P10683
    RAWVAWR-NH2 646044-31-7 98%
    RAWVAWR-NH2 is a peptide derived from human lysozyme with antibacterial activity.
    RAWVAWR-NH2
  • HY-P10684
    Polyphemusin II 125139-68-6 98%
    Polyphemusin II is an antimicrobial peptide which can be isolated from Limulus polyphemus hemocytes. Polyphemusin II exhibits antimicrobial activities against various Gram (+)/(-) bacteria and fungi.
    Polyphemusin II
  • HY-P10685
    T-22 147658-54-6 98%
    T-22 (polyphemusin II with [Tyr5,12,Lys7]) is a new synthetic peptide that fights HIV, with an EC50 of 0.008 μg/mL and a CC50 of 54 μg/mL. T22 promotes plant height, photosynthesis, total chlorophyll content, and gas exchange in tomatoes, and it can resist CMV.
    T-22
  • HY-P10688
    NQK-Q8 peptide 2445453-91-6 98%
    NQK-Q8 peptide is an immunodominant peptide of SARS-Cov-2.
    NQK-Q8 peptide
  • HY-P10689
    NQK-A8 peptide 98%
    NQK-A8 peptide is an immunodominant peptide of seasonal coronaviruses HKU1-CoV and OC43-CoV.
    NQK-A8 peptide
  • HY-P10691
    P-113D 348641-28-1 98%
    P-113D is an antimicrobial peptide that targets Pseudomonas aeruginosa, showing good antibacterial activity and can be used in cystic fibrosis research, the MIC for P-113D against ATCC 27853 is 3.1 μg/mL.
    P-113D
  • HY-P10693
    CZEN-002 942626-41-7 98%
    CZEN-002 is a derivative of alpha-melanocyte-stimulating hormone that has anti-inflammatory and antibacterial properties, inhibiting the production of TNF-α.
    CZEN-002
  • HY-P10694
    IDR-HH2 1214699-22-5 98%
    IDR-HH2 is an immunomodulatory peptide with the ability to modulate the host cytokine/chemokine environment. IDR-HH2 can promote the adhesion of monocytes and THP-1 cells to fibronectin. Additionally, IDR-HH2 possesses antibacterial activity, inhibiting the activity of both P. aeruginosa and S. aureus with MIC values of 75 µg/mL and 38 µg/mL, respectively.
    IDR-HH2
  • HY-P10695
    Bac8c 1391837-43-6 98%
    Bac8c is an antimicrobial peptide with strong antibacterial activity against Gram-negative and Gram-positive bacteria. The MIC of Bac8c against S. aureus, MRSA, S. epidermidis, E. coli, and P. aeruginosa are 2, 8, 4, 4, and 4 μg/mL, respectively.
    Bac8c
  • HY-P10696
    C16G2 2154327-48-5 98%
    C16G2 is a specific targeted antimicrobial peptide (STAMP) that targets the cariogenic oral pathogen Streptococcus mutans. C16G2 specifically recognizes and disrupts the bacterial cell membrane, causing small molecule leakage and loss of membrane potential, leading to bacterial killing. C16G2 exhibits higher selectivity and efficacy against Streptococcus mutans, unlike broad-spectrum antimicrobial peptides.
    C16G2
  • HY-P10700
    RO7196472 2097285-98-6 98%
    RO7196472 is a potent and selective macrocyclic peptide antibiotic that targets Acinetobacter strains. RO7196472 inhibits Acinetobacter strain activity by specifically binding to the Lipopolysaccharide (LPS) binding site on the LptB2FG complex located on the inner membrane of Acinetobacter strains, thereby blocking LPS transport and suppressing Acinetobacter strain activity.
    RO7196472
  • HY-P10721
    Plectasin 98%
    Plectasin is a peptide antibiotic derived from saprophytic fungi. Plectasin can kill pneumococcus in vitro. Plectasin can alleviate experimental peritonitis and pneumonia caused by pneumococcus in mice.
    Plectasin
Cat. No. Product Name / Synonyms Application Reactivity