T-22
T-22 (polyphemusin II with [Tyr5,12,Lys7]) is a new synthetic peptide that fights HIV, with an EC50 of 0.008 μg/mL and a CC50 of 54 μg/mL. T22 promotes plant height, photosynthesis, total chlorophyll content, and gas exchange in tomatoes, and it can resist CMV.
For research use only. We do not sell to patients.
- CAS No.: 147658-54-6
- Formula: C109H164N38O22S4
- Molecular Weight:2486.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 147658-54-6
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Molecular Weight 2486.97
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Formula C109H164N38O22S4
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Synonyms
[Tyr5,12,Lys7]-Polyphemusin II
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Sequence
Arg-Arg-Trp-Cys-Tyr-Arg-Lys-Cys-Tyr-Lys-Gly-Tyr-Cys-Tyr-Arg-Lys-Cys-Arg-NH2 (Disulfide bridge: Cys4-Cys17,Cys8-Cys13)
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Sequence Shortening
RRWCYRKCYKGYCYRKCR-NH2 (Disulfide bridge: Cys4-Cys17,Cys8-Cys13)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. Masao Masuda, et al. A novel anti-HIV synthetic peptide, T-22 ([Tyr5,12,Lys7]-polyphemusin II). Biochemical and Biophysical Research Communications. Volume 189, Issue 2, 15 December 1992, Pages 845-850. [Content Brief]
[2]. Antonella Vitti, et al. Trichoderma harzianum T-22 Induces Systemic Resistance in Tomato Infected by Cucumber mosaic virus. Front Plant Sci. 2016 Oct 10:7:1520. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
T-22 Related Classifications
HY-P10685 Related Classifications
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