147658-54-6
Chemical Structure
T-22
Synonym(s): [Tyr5,12,Lys7]-Polyphemusin II
- CAS No.: 147658-54-6
- Formula:C109H164N38O22S4
- Molecular Weight:2486.97
SMILES: C([C@@H](C(N[C@@H]1C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@]3(C(=O)N[C@@H](CC4=CC=C(O)C=C4)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CC5=CC=C(O)C=C5)C(=O)N[C@@](CSSC3)(C(=O)N[C@@H](CC6=CC=C(O)C=C6)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CSSC1)[H])[H])=O)NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)C=7C=8C(NC7)=CC=CC8
Biological Activity: T-22 (polyphemusin II with [Tyr5,12,Lys7]) is a new synthetic peptide that fights HIV, with an EC50 of 0.008 μg/mL and a CC50 of 54 μg/mL. T22 promotes plant height, photosynthesis, total chlorophyll content, and gas exchange in tomatoes, and it can resist CMV[1][2].
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T-22 | T-22 (polyphemusin II with [Tyr5,12,Lys7]) is a new synthetic peptide that fights HIV, with an EC50 of 0.008 μg/mL and a CC50 of 54 μg/mL. T22 promotes plant height, photosynthesis, total chlorophyll content, and gas exchange in tomatoes, and it can resist CMV. | |||||||||||||||||||||
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References
- [1]. Masao Masuda, et al. A novel anti-HIV synthetic peptide, T-22 ([Tyr5,12,Lys7]-polyphemusin II). Biochemical and Biophysical Research Communications. Volume 189, Issue 2, 15 December 1992, Pages 845-850. [Content Brief]
- [2]. Antonella Vitti, et al. Trichoderma harzianum T-22 Induces Systemic Resistance in Tomato Infected by Cucumber mosaic virus. Front Plant Sci. 2016 Oct 10:7:1520. [Content Brief]
