IDR-HH2
IDR-HH2 is an immunomodulatory peptide with the ability to modulate the host cytokine/chemokine environment. IDR-HH2 can promote the adhesion of monocytes and THP-1 cells to fibronectin. Additionally, IDR-HH2 possesses antibacterial activity, inhibiting the activity of both P. aeruginosa and S. aureus with MIC values of 75 µg/mL and 38 µg/mL, respectively.
For research use only. We do not sell to patients.
- CAS No.: 1214699-22-5
- Formula: C62H117N23O13
- Molecular Weight:1392.74
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1214699-22-5
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Molecular Weight 1392.74
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Formula C62H117N23O13
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Sequence
Val-Gln-Leu-Arg-Ile-Arg-Val-Ala-Val-Ile-Arg-Ala-NH2
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Sequence Shortening
VQLRIRVAVIRA-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Madera L, et al. Synthetic immunomodulatory peptide IDR-1002 enhances monocyte migration and adhesion on fibronectin[J]. Journal of innate immunity, 2012, 4(5-6): 553-568. [Content Brief]
[2]. Rivas-Santiago B, et al. Ability of innate defence regulator peptides IDR-1002, IDR-HH2 and IDR-1018 to protect against Mycobacterium tuberculosis infections in animal models[J]. PloS one, 2013, 8(3): e59119. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IDR-HH2 Related Classifications
HY-P10694 Related Classifications
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