2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P99753
    Nerelimomab 162774-06-3
    Nerelimomab (BAYX1351) is an anti-TNF-α antibody. Nerelimomab can be used for research of sepsis.
    Nerelimomab
  • HY-P99800
    Pritoxaximab 1351470-16-0
    Pritoxaximab is an IgG1κ antibody targeting shiga toxin type 1.
    Pritoxaximab
  • HY-Q40175
    Antitrypanosomal agent 9 438474-67-0
    Antitrypanosomal agent 9 (compound 1) is a potent antitrypanosomal agent. Antitrypanosomal agent 9 shows inhibitory activity against T. b. brucei, with an IC50 of 1.15 μM. Antitrypanosomal agent 9 can be used for human African trypanosomiasis (HAT) research.
    Antitrypanosomal agent 9
  • HY-Q50147
    Antimicrobial agent-21 724746-07-0 98.35%
    Antimicrobial agent-21 (Compound IIm) is a bacterial inhibitor. Antimicrobial agent-21 is active against gram-positive and gram-negative bacterial.
    Antimicrobial agent-21
  • HY-U00007
    Stilbamidine 122-06-5 98%
    Stilbamidine is a diamidine compound derived from Stilbene and used chiefly in the form of its crystalline isethionate salt in treating various fungal infections.
    Stilbamidine
  • HY-U00029
    BC-3205 hydrochloride 404577-28-2 98%
    BC-3205 hydrochloride is an anti-amoeba agent. BC-3205 hydrochloride inhibits N. fowleri.
    BC-3205 hydrochloride
  • HY-Y0055S
    Phenothiazine-d8 1219803-41-4 99.0%
    Phenothiazine-d8 is the deuterium labeled Phenothiazine. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases.
    Phenothiazine-d8
  • HY-Y0061R
    Oxindole (Standard) 59-48-3 98%
    Oxindole (Standard) is the analytical standard of Oxindole. This product is intended for research and analytical applications. Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.
    Oxindole (Standard)
  • HY-Y0073R
    4-Hydroxyacetophenone (Standard) 99-93-4 99.89%
    4-Hydroxyacetophenone (Standard) is the analytical standard of 4-Hydroxyacetophenone. This product is intended for research and analytical applications. 4-Hydroxyacetophenone (P-hydroxyacetophenone) is a major hepatoprotective and choleretic compound found in Artemisia and Illicium plants, exhibiting antiviral and anti-inflammatory effects against hepatitis B virus. Additionally, 4-Hydroxyacetophenone inhibits cancer cell adhesion, invasion, and migration by remodeling actin. 4-Hydroxyacetophenone holds promise for research in the fields of inflammatory diseases and cancer.
    4-Hydroxyacetophenone (Standard)
  • HY-Y0084S
    3,4,5-Trimethoxybenzoic acid-d3 84759-05-7 98%
    3,4,5-Trimethoxybenzoic acid-d3 is the deuterium labeled 3,4,5-Trimethoxybenzoic acid[1]. 3,4,5-Trimethoxybenzoic acid (Eudesmic acid;Trimethylgallic Acid) is a benzoic acid derivative. A building block in medicine and organic synthesis. 3,4,5-Trimethoxybenzoic acid exhibits antibacterial activity against S. aureus with MIC of 0.97 μg/mL.
    3,4,5-Trimethoxybenzoic acid-d3
  • HY-Y0148R
    10-Hydroxydecanoic acid (Standard) 1679-53-4 98%
    10-Hydroxydecanoic acid (Standard) is the analytical standard of 10-Hydroxydecanoic acid. This product is intended for research and analytical applications. 10-Hydroxydecanoic acid (10-HDAA) is a saturated fatty acid derived from 10-hydroxy-trans-2-decenoic acid, which can be isolated from royal jelly. 10-Hydroxydecanoic acid exhibits various biological activities, including anti-inflammatory, insecticidal, anti-malarial, and anti-Leishmania properties, as well as enhancing antigen-specific immune responses. The anti-inflammatory effects of 10-Hydroxydecanoic acid are primarily mediated by inhibiting the activation of NF-κB and the translation of interferon regulatory factor 1 (IRF-1), which reduces the production of interleukin 6 (IL-6) and nitric oxide (NO) in inflammatory cells. Additionally, 10-Hydroxydecanoic acid alleviates neuroinflammatory responses through the p53-autophagy pathway and the p53-NLRP3 pathway. Finally, 10-Hydroxydecanoic acid enhances antigen-specific immune responses by promoting the effective uptake of antigens by microfold cells[1][2][3][4][5].
    10-Hydroxydecanoic acid (Standard)
  • HY-Y0152A
    Cinchonine monohydrochloride hydrate 206986-88-1 98%
    Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural compound which has been effectively used as antimalarial agent. Cinchonine monohydrochloride hydrate activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine monohydrochloride hydrate is also an inhibitor of human platelet aggregation. Cinchonine monohydrochloride hydrate possesses a suppressive effect on adipogenesis.
    Cinchonine monohydrochloride hydrate
  • HY-Y0191R
    α-Pyridone (Standard) 142-08-5 98%
    α-Pyridone (Standard) is the analytical standard of α-Pyridone. This product is intended for research and analytical applications. α-Pyridone (2-Pyridone) is an antibacterial agent. α-Pyridone can be synthesized via the 1,4-addition of 2-(phenylsulfinyl)acetamide to α,β-unsaturated ketones followed by cyclization and sulfoxide elimination. α-Pyridone can also be used to synthesize a wide range of heterocyclic compounds.
    α-Pyridone (Standard)
  • HY-Y0191S
    α-Pyridone-d5 98%
    α-Pyridone-d5 (2-Pyridone-d5) is the deuterium labeled α-Pyridone (HY-Y0191). α-Pyridone (2-Pyridone) is an antibacterial agent. α-Pyridone can be synthesized via the 1,4-addition of 2-(phenylsulfinyl)acetamide to α,β-unsaturated ketones followed by cyclization and sulfoxide elimination. α-Pyridone can also be used to synthesize a wide range of heterocyclic compounds.
    α-Pyridone-d5
  • HY-Y0219A
    1,2,4-Triazole sodium 41253-21-8
    1,2,4-Triazole (sodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    1,2,4-Triazole sodium
  • HY-Y0319D
    Acetic acid lead 546-67-8 98%
    Acetic acid lead is a carboxylic acid and short-chain fatty acid (SCFAs). Magnesium acetate tetrahydrate activates AMPK, increases ROS, cleaved caspase 9, PPARα, downregulates SREBP-1c, ChREBP expression. Acetic acid lead exhibits antifungal activity against Saccharomyces cerevisiae W303-1A. Acetic acid lead regulates energy metabolism. Acetic acid lead has anticancer activity against gastric cancer. Acetic acid lead induces writhing reaction and ulcerative colitis. Acetic acid lead can be used in the researches for gastric cancer, ulcerative colitis, hepatic steatosis, and pain.
    Acetic acid lead
  • HY-Y0320E
    Dimethyl sulfoxide (suitable for HPLC) 67-68-5 98%
    Dimethyl sulfoxide (suitable for HPLC) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide (suitable for HPLC) is suitable for HPLC.
    Dimethyl sulfoxide (suitable for HPLC)
  • HY-Y0403R
    3-Chlorobenzoic acid (Standard) 535-80-8 98%
    3-Chlorobenzoic acid (Standard) is the analytical standard of 3-Chlorobenzoic acid. This product is intended for research and analytical applications. 3-Chlorobenzoic acid (m-Chlorobenzoic acid) is the only carbon source for the bacterium.
    3-Chlorobenzoic acid (Standard)
  • HY-Y0442S
    2-Methylbenzaldehyde-13C 138151-99-2 98.7%
    2-Methylbenzaldehyde-13C is the 13C labeled 2-Methylbenzaldehyde (HY-Y0442). 2-Methylbenzaldehyde is an acaricide found in Morinda officinalis. 2-Methylbenzaldehyde exerts fumigant and contact acaricidal activity against Dermatophagoides farinae, Dermatophagoides pteronyssinus, and Haemaphysalis longicornis. 2-Methylbenzaldehyde can be used for the research of severe fever with thrombocytopenia syndrome.
    2-Methylbenzaldehyde-13C
  • HY-Y0507R
    DL-Serine (Standard) 302-84-1 98%
    DL-Serine (Standard) is the analytical standard of DL-Serine. This product is intended for research and analytical applications. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV)[1].
    DL-Serine (Standard)
Cat. No. Product Name / Synonyms Application Reactivity