10-Hydroxydecanoic acid (Standard)
10-Hydroxydecanoic acid (Standard) is the analytical standard of 10-Hydroxydecanoic acid. This product is intended for research and analytical applications. 10-Hydroxydecanoic acid (10-HDAA) is a saturated fatty acid derived from 10-hydroxy-trans-2-decenoic acid, which can be isolated from royal jelly. 10-Hydroxydecanoic acid exhibits various biological activities, including anti-inflammatory, insecticidal, anti-malarial, and anti-Leishmania properties, as well as enhancing antigen-specific immune responses. The anti-inflammatory effects of 10-Hydroxydecanoic acid are primarily mediated by inhibiting the activation of NF-κB and the translation of interferon regulatory factor 1 (IRF-1), which reduces the production of interleukin 6 (IL-6) and nitric oxide (NO) in inflammatory cells. Additionally, 10-Hydroxydecanoic acid alleviates neuroinflammatory responses through the p53-autophagy pathway and the p53-NLRP3 pathway. Finally, 10-Hydroxydecanoic acid enhances antigen-specific immune responses by promoting the effective uptake of antigens by microfold cells[1][2][3][4][5].
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- Purity : 98%
- CAS No.: 1679-53-4
- 화학식: C10H20O3
- 분자량:188.26
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
신청
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1679-53-4
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분자량 188.26
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화학식 C10H20O3
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SMILES
O=C(O)CCCCCCCCCO
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Synonyms
NSC 15139 (Standard); 10-HDAA (Standard)
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- 10-Hydroxydecanoic acid (Standard)
- 1679-53-4
- NSC 15139 (Standard)
- 10-HDAA (Standard)
- Reference Standards
- Parasite
- Autophagy
- NF-κB
- Interleukin Related
- NO Synthase
- MDM-2/p53
- TNF Receptor
- RANKL/RANK
- Caspase
- Nuclear factor-κB
- Nuclear factor-kappaB
- IL
- Nitric oxide synthases
- NOS
- Tumor Necrosis Factor Receptor
- TNFR
- Inhibitor
- inhibitor
- inhibit