Phenothiazine-d8
Based on 1 Customer Validation
Phenothiazine-d8 is the deuterium labeled Phenothiazine. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 1219803-41-4
- Formula: C12HD8NS
- Molecular Weight:207.32
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1219803-41-4
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Unlabeled Cas 92-84-2
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Appearance Solid
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Molecular Weight 207.32
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Formula C12HD8NS
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Color Light yellow to yellow
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SMILES
[2H]C1=C2SC3=C([2H])C([2H])=C([2H])C([2H])=C3NC2=C([2H])C([2H])=C1[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (482.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Gao YQ, et al. Isolation and Characterization of Antifungal Metabolites from the Melia azedarach-Associated Fungus Diaporthe eucalyptorum. J Agric Food Chem. 2020 Feb 26;68(8):2418-2425. [Content Brief]
[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[3]. Mitchell SC, et, al. The toxicity of phenothiazine. Drug Metabol Drug Interact. 1994;11(3):201-35. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8235 mL | 24.1173 mL | 48.2346 mL | 120.5865 mL |
| 5 mM | 0.9647 mL | 4.8235 mL | 9.6469 mL | 24.1173 mL | |
| 10 mM | 0.4823 mL | 2.4117 mL | 4.8235 mL | 12.0587 mL | |
| 15 mM | 0.3216 mL | 1.6078 mL | 3.2156 mL | 8.0391 mL | |
| 20 mM | 0.2412 mL | 1.2059 mL | 2.4117 mL | 6.0293 mL | |
| 25 mM | 0.1929 mL | 0.9647 mL | 1.9294 mL | 4.8235 mL | |
| 30 mM | 0.1608 mL | 0.8039 mL | 1.6078 mL | 4.0196 mL | |
| 40 mM | 0.1206 mL | 0.6029 mL | 1.2059 mL | 3.0147 mL | |
| 50 mM | 0.0965 mL | 0.4823 mL | 0.9647 mL | 2.4117 mL | |
| 60 mM | 0.0804 mL | 0.4020 mL | 0.8039 mL | 2.0098 mL | |
| 80 mM | 0.0603 mL | 0.3015 mL | 0.6029 mL | 1.5073 mL | |
| 100 mM | 0.0482 mL | 0.2412 mL | 0.4823 mL | 1.2059 mL |
Phenothiazine-d8 Related Classifications
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