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Cat. No.: HY-Y0152A

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Cinchonine monohydrochloride hydrate

(Synonyms: (8R,9S)-Cinchonine monohydrochloride hydrate; LA40221 monohydrochloride hydrate)

5 Cited Publications

Customer Review

Based on 5 publication(s) in Google Scholar

Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural compound which has been effectively used as antimalarial agent. Cinchonine monohydrochloride hydrate activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine monohydrochloride hydrate is also an inhibitor of human platelet aggregation. Cinchonine monohydrochloride hydrate possesses a suppressive effect on adipogenesis.

For research use only. We do not sell to patients.

CAS No.: 206986-88-1
Formula: C₁₉H₂₂N₂O.HCl.xH₂O

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Cinchonine monohydrochloride hydrate Chemical Structure

CAS No.: 206986-88-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

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Chemical Information

CAS No. 206986-88-1
Formula C₁₉H₂₂N₂O.HCl.xH₂O
SMILES

O[C@@H](C1=CC=NC2=CC=CC=C12)[C@]3([H])[N@@]4C[C@H](C=C)[C@@H](CC4)C3.[H]Cl.[x].O
Synonyms

(8R,9S)-Cinchonine monohydrochloride hydrate; LA40221 monohydrochloride hydrate
Structure Classification
- Alkaloids
- Quinoline Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (5)

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Int J Biol Macromol

The interaction of cinchonine and immunoglobulin G and the development of a nanocomplex with improved anti-breast cancer activity. [Abstract]

2025 Jan:287:138152. PMID: 39613056
Diabetes Obes Metab

AdipoRon attenuates steatosis, inflammation and fibrosis in murine diet-induced NASH via inhibiting ER stress. [Abstract]

2025 Jun 17. PMID: 40528684
Respir Res

Lactate activates ER stress to promote alveolar epithelial cells apoptosis in pulmonary fibrosis. [Abstract]

2024 Nov 9;25(1):401. PMID: 39522031
Front Cell Infect Microbiol

Inhibition of Porcine Epidemic Diarrhea Virus by Cinchonine via Inducing Cellular Autophagy. [Abstract]

2022 Jun 14:12:856711. PMID: 35774410
Biomed Pharmacother

Cinchonine exerts anti-tumor and immunotherapy sensitizing effects in lung cancer by impairing autophagic-lysosomal degradation. [Abstract]

2023 Aug:164:114980. PMID: 37301135

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jin ZL, et, al. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Exp Ther Med. 2018 Jun;15(6):5046-5050. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Cinchonine monohydrochloride hydrate

5 Cited Publications

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Publications (5)
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Cinchonine monohydrochloride hydrate

Publications Citing Use of MedChemExpress (MCE) Cinchonine monohydrochloride hydrate

All Parasite Isoforms

Biological Activity

Chemical Information

Publications (5)

Purity & Documentation

References

Calculators

Help & FAQs

Cinchonine monohydrochloride hydrate Related Classifications

HY-Y0152A Related Classifications