2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P992482
    VIR-2482 98%
    VIR-2482 is a monoclonal antibody targeting influenza A hemagglutinin (HA). VIR-2482 is generated by introducing LS mutations (M428L/N434S) into the Fc region of MEDI8852 (HY-P991446). VIR-2482 binds to the conserved HA stem epitope across all 18 influenza A HA subtypes, neutralizes a broad spectrum of H1N1 and H3N2 strains, binds to FcγRIIIa, FcγRIIa and C1q, and induces antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. VIR-2482 reduces morbidity and mortality caused by seasonal influenza A strains and provides prophylactic protection in mice. VIR-2482 can be used in research related to influenza A disease.
    VIR-2482
  • HY-U00035R
    MGB-BP-3 (Standard) 1000277-08-6
    Sinapine (thiocyanate) (Standard) is the analytical standard of Sinapine (thiocyanate). This product is intended for research and analytical applications. Sinapine thiocyanate is an alkaloid isolated from seeds of the cruciferous species. Sinapine thiocyanate exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine thiocyanate is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease.
    MGB-BP-3 (Standard)
  • HY-U00058R
    Diflucortolone valerate (Standard) 59198-70-8
    Diflucortolone valerate (Standard) is the analytical standard of Diflucortolone valerate. This product is intended for research and analytical applications. Diflucortolone valerate is a powerful corticosteroid used topically for the research of various skin diseases.
    Diflucortolone valerate (Standard)
  • HY-U00075A
    Indanazoline hydrochloride 40507-80-0 98%
    Indanazoline (hydrochloride) is an orally active imidazoline derivative. Indanazoline (hydrochloride) has a LD50 of 481 mg/kg in rat model. Indanazoline (hydrochloride) can be studied in research on rhinitis.
    Indanazoline hydrochloride
  • HY-U00154R
    Cefuracetime (Standard) 39685-31-9
    Cefuracetime (Standard) (SKF81367 (Standard)) is the analytical standard of Cefuracetime (HY-U00154). This product is intended for research and analytical applications. Cefuracetime is a cephalosporin antibiotic.
    Cefuracetime (Standard)
  • HY-U00295A
    Melarsonyl dipotassium 13355-00-5 98%
    Melarsonyl dipotassium (Melarsonic acid dipotassium) is an anthelmintic agent which can inhibit parasite potently.
    Melarsonyl dipotassium
  • HY-W007704
    Methyl cyclohexanecarboxylate 4630-82-4 99.29%
    Methyl cyclohexanecarboxylate is a compound related to 2-cyclohexenylcarbonyl CoA. Methyl cyclohexanecarboxylate is produced during the incubation of 2-cyclohexenylcarbonyl CoA with cell-free extracts of Streptomyces collinus.
    Methyl cyclohexanecarboxylate
  • HY-W010203
    2-Decanone 693-54-9 98%
    2-Decanone is an antifungal agent. 2-Decanone inhibits pathogen mycelial growth, spore germination, and appressorium formation. 2-Decanone downregulates spore germination-related genes (MfBmp1) and penetration structure formation genes (MfPls1), inducing reactive oxygen species (ROS) accumulation to trigger mitochondrial damage and subsequent spore apoptosis. 2-Decanone is promising for research of postharvest disease control in fruits and vegetables.
    2-Decanone
  • HY-W010235
    3,5-Dimethoxytoluene 4179-19-5
    3,5-Dimethoxytoluene, a methylated phenolic derivative, is one of characteristic scent compounds emitted from flowers of most rose varieties. 3,5-Dimethoxytoluene shows significant fumigant toxicity against L. serricorne and L. bostrychophila with LC50 values of 4.99 mg/L air and 0.91 mg/L air, respectively.
    3,5-Dimethoxytoluene
  • HY-W011581
    6,9-Dichloro-2-methoxyacridine 86-38-4 98%
    6,9-Dichloro-2-methoxyacridine is an aromatic heterocyclic compound. 6,9-Dichloro-2-methoxyacridine is a precursor of ACS03, which exhibits antileishmanial and antitumor activities.
    6,9-Dichloro-2-methoxyacridine
  • HY-W012346
    Geranyl isobutyrate 2345-26-8
    Geranyl isobutyrate is a synthetic α,β‑unsaturated branched‑chain aliphatic ester and a geraniol derivative. Geranyl isobutyrate acts as a food and feed flavouring agent and a biologically active antimicrobial compound. Geranyl isobutyrate shows antimicrobial activity against Gram‑positive and most Gram‑negative bacteria.
    Geranyl isobutyrate
  • HY-W012475
    cis-3-Hexenyl benzoate 25152-85-6 98%
    cis-3-Hexenyl benzoate is a volatile organic compound with a grassy aroma, widely used in the fragrance and cosmetic industries. It exhibits weak antifungal activity. cis-3-Hexenyl benzoate shows no significant risks in genotoxicity, reproductive toxicity, or environmental toxicity, and its skin sensitization potential is controllable within defined concentration limits.
    cis-3-Hexenyl benzoate
  • HY-W013767
    Thiodicarb 59669-26-0 98%
    Thiodicarb is a carbamate insecticide used to control flies in animal and poultry houses and dairies. Thiodicarb is metabolized into methomyl in animals and plants, and subsequently degraded into carbon dioxide and acetonitrile.
    Thiodicarb
  • HY-W016584
    4,5-Dichlorocatechol 3428-24-8 98%
    4,5-Dichlorocatechol is a substrate of the broad-spectrum chlorocatechol 1,2-dioxygenase of pseudomonas chlororaphis RW71. The Ki values for 4,5-dichlorocatechol is 30 nM for the dioxygenase of the Chlorobenzoate-degrading strain Pseudomonas putida AC27 and 4 nM for the dioxygenase of Acidovorax sp. strain PS14.
    4,5-Dichlorocatechol
  • HY-W016937
    Moroxydine 3731-59-7 98%
    Moroxydine (ABOB) is a broad-spectrum agent with multi-antiviral activities against DNA and RNA viruses, including influenza virus, herpes simplex, varicella zoster, measles, mumps disease, hepatitis C virus, etc. Moroxydine exhibits excellent antiviral activity and shows low cytotoxicity to cells infected by dsRNA viruses (grass carp reovirus, GCRV) and large DNA viruses (giant salamander iridovirus, GSIV). Moroxydine blocks the GCRV-induced cytopathic effects and eliminates nucleocapsids in ctenopharyngodon idella kidney (CIK) cells to keep the normal morphological structure. Moroxydine significantly inhibits the apoptosis, the caspase 3 activity, Bax expression and down-regulates Bcl-2 levels[1][2][3].
    Moroxydine
  • HY-W017143
    Antifungal agent 158 27593-23-3 98%
    Antifungal agent 158 is an α-pyrone derivative that can be found in Trichoderma harzianum, exhibiting antifungal activity against select plant-pathogenic fungi, including Chaetomium spp., Curvularia lunata, and Aspergillus flavus. Antifungal agent 158 is non-toxic to greenhouse-grown bean, corn, and tobacco plants. Antifungal agent 158 can be used for research on Aspergillus flavus infection.
    Antifungal agent 158
  • HY-W023253
    Biclotymol 15686-33-6 98%
    Biclotymol is an antimicrobial agent against gram-positive cocci. Biclotymol inhibits Streptococcus pneumoniae and Haemophilus influenzae, with MIC of 150 and 150 μM. Biclotymol exhibits anti-inflammatory and analgesic activity and ameliorates the otolaryngology infection and throat sore.
    Biclotymol
  • HY-W024297
    VP-4509 2190144-51-3 98%
    VP-4509, an anti-methicillin‐resistant Staphylococcus aureus (MRSA) agent, with the MIC of 49.3 µM. VP-4509 also possesses high antibacterial activity towards gram-negative bacteria P. aeruginosa.
    VP-4509
  • HY-W026467
    MMV665916 896356-25-5 98%
    MMV665916, a quinazolinedione derivative, is an antimalarial agent. MMV665916 displays antiplasmodial activity against P. falciparum FcB1 strain with EC50 value of 0.4 μM and presents the high selectivity index (SI>250).
    MMV665916
  • HY-W026644
    Acridine-9-carboxaldehyde 885-23-4 98.0%
    Acridine-9-carboxaldehyde (Acridine-9-carbaldehyde) is a bioactive compound with potential antibacterial and antitumor activities. Acridine-9-carboxaldehyde is widely used as a building block in compound development to synthesize various bioactive derivatives. Acridine-9-carboxaldehyde exhibits significant cytotoxicity against certain cancer cells, making it an important candidate in cancer inhibition research.
    Acridine-9-carboxaldehyde
Cat. No. Product Name / Synonyms Application Reactivity