cis-3-Hexenyl benzoate
Based on 1 Customer Validation
cis-3-Hexenyl benzoate is a volatile organic compound with a grassy aroma, widely used in the fragrance and cosmetic industries. It exhibits weak antifungal activity. cis-3-Hexenyl benzoate shows no significant risks in genotoxicity, reproductive toxicity, or environmental toxicity, and its skin sensitization potential is controllable within defined concentration limits.
For research use only. We do not sell to patients.
- Purity: 98.05%
- CAS No.: 25152-85-6
- Formula: C13H16O2
- Molecular Weight:204.26
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
cis-3-hexenyl benzoate (0-5000 μg/plate; as per assay protocol) is not mutagenic in the Ames test using Salmonella typhimurium strains TA98, TA100, TA1535, TA1537, and Escherichia coli strain WP2uvrA[1].
cis-3-hexenyl benzoate (0-650 μg/mL; 4 h) is non-clastogenic in the in vitro micronucleus test using human peripheral blood lymphocytes[1].
cis-3-hexenyl benzoate (10 days) exhibits poor antifungal activity against Alternaria alternata, Botrytis cinerea, and Magnaporthe oryzae, with inhibition rates of 7.90%, 17.94%, and 9.76% respectively, and no activity against other tested plant fungal pathogens[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 25152-85-6
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Appearance Liquid (Density: 0.999 g/cm3)
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Molecular Weight 204.26
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Formula C13H16O2
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Color Colorless to light yellow
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SMILES
O=C(OCC/C=C\CC)C1=CC=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (489.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: 5 mg/mL (24.48 mM); Suspended solution; Need ultrasonic
This protocol yields a suspended solution of 5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (24.48 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (597 KB)
- English - EN (597 KB)
- Français - FR (597 KB)
- Deutsch - DE (597 KB)
- Norwegian - NO (597 KB)
- Español - ES (597 KB)
- Swedish - SV (597 KB)
- Italian - IT (597 KB)
- Korean - KR (597 KB)
- Portuguese - PT (597 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 4.8957 mL | 24.4786 mL | 48.9572 mL | 122.3930 mL |
| 5 mM | 0.9791 mL | 4.8957 mL | 9.7914 mL | 24.4786 mL | |
| 10 mM | 0.4896 mL | 2.4479 mL | 4.8957 mL | 12.2393 mL | |
| 15 mM | 0.3264 mL | 1.6319 mL | 3.2638 mL | 8.1595 mL | |
| 20 mM | 0.2448 mL | 1.2239 mL | 2.4479 mL | 6.1197 mL | |
| 25 mM | 0.1958 mL | 0.9791 mL | 1.9583 mL | 4.8957 mL | |
| 30 mM | 0.1632 mL | 0.8160 mL | 1.6319 mL | 4.0798 mL | |
| 40 mM | 0.1224 mL | 0.6120 mL | 1.2239 mL | 3.0598 mL | |
| 50 mM | 0.0979 mL | 0.4896 mL | 0.9791 mL | 2.4479 mL | |
| 60 mM | 0.0816 mL | 0.4080 mL | 0.8160 mL | 2.0399 mL | |
| 80 mM | 0.0612 mL | 0.3060 mL | 0.6120 mL | 1.5299 mL | |
| 100 mM | 0.0490 mL | 0.2448 mL | 0.4896 mL | 1.2239 mL |
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