Antifungal agent 158
Based on 1 Customer Validation
Antifungal agent 158 is an α-pyrone derivative that can be found in Trichoderma harzianum, exhibiting antifungal activity against select plant-pathogenic fungi, including Chaetomium spp., Curvularia lunata, and Aspergillus flavus. Antifungal agent 158 is non-toxic to greenhouse-grown bean, corn, and tobacco plants. Antifungal agent 158 can be used for research on Aspergillus flavus infection.
For research use only. We do not sell to patients.
- Purity: 99.32%
- CAS No.: 27593-23-3
- Formula: C10H14O2
- Molecular Weight:166.22
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Storage:
RT, stored under nitrogen.
In solvent -80°C, 1 year , -20°C, 6 months
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| SH-SY5Y | EC50 |
1.28 μM
Compound: 2
|
Neuroprotective activity against 6-OHDA induced cell death in human SH-SY5Y cells preincubated with 6-hyrdoxydopamine followed by compound addition and measured after 24 hrs by MTT assay
Neuroprotective activity against 6-OHDA induced cell death in human SH-SY5Y cells preincubated with 6-hyrdoxydopamine followed by compound addition and measured after 24 hrs by MTT assay
|
[PMID: 35968659] |
Antifungal agent 158 (compound 6-Pentyl-α-pyrone) (10-6-10-3 M) significantly inhibits the growth of etiolated wheat coleoptiles (Triticum aestivum L., cv. Wakeland) at 10-3 M[1].
Antifungal agent 158 (1:50-1:10 dilutions in acetone) inhibits the growth of Chaetomium cochlioides 195, Chaetomium cochlioides 189, Chaetomium spinosum 193, Curvularia lunata 49, Aspergillus flavus, and Escherichia coli at specific dilutions (1:10 to 1:40) but does not inhibit Bacillus subtilis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 27593-23-3
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Appearance Liquid (Density: 1.004 g/cm3)
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Molecular Weight 166.22
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Formula C10H14O2
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SMILES
CCCCCC(O1)=CC=CC1=O
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Structure Classification
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Initial Source
Trichoderma harzianum
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, stored under nitrogen
In solvent -80°C 1 year -20°C 6 months
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)