2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-156427
    Antileishmanial agent-25 98%
    Antileishmanial agent-25 (compound 24) is selective antileishmanial activity on intracellular amastigotes, with the IC50 of 6.63 μM.
    Antileishmanial agent-25
  • HY-156440
    7-51A 98%
    7-51A is a potent PB2 inhibitor with a KD value of 1.64 nM as determined by ITC. PB2 is an essential subunit of influenza RNA-dependent RNA polymerase (RdRP).
    7-51A
  • HY-156456
    Elastase LasB-IN-1 2762675-17-0 98%
    Elastase LasB-IN-1 (Compound 4b) has antibacterial activity. Elastase LasB-IN-1 (Compound 4b) is a selective elastase LasB inhibitor with an IC50 value of 76 nM.
    Elastase LasB-IN-1
  • HY-156462
    Topoisomerase I inhibitor 9 1228150-86-4 98%
    Topoisomerase I inhibitor 9 (compound 3d) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 9 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 34.81μM.
    Topoisomerase I inhibitor 9
  • HY-156464
    Topoisomerase I inhibitor 10 98%
    Topoisomerase I inhibitor 10 (compound 13) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 10 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 27.91 μM.
    Topoisomerase I inhibitor 10
  • HY-15662R
    Tulathromycin A (Standard) 217500-96-4 98%
    Tulathromycin A (Standard) is the analytical standard of Tulathromycin A. This product is intended for research and analytical applications. Tulathromycin A (Tulathromycin), a macrolide antibiotic, inhibits protein synthesis (IC50=0.26 μM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects.
    Tulathromycin A (Standard)
  • HY-156975
    Sulfatrozole 13369-07-8 98%
    Sulfatrozole is a sulfanilamide derivative. Sulfatrozole is an antimicrobial agent with broad-spectrum activity.
    Sulfatrozole
  • HY-157022
    SARS-CoV-2-IN-67 2997784-47-9 98%
    SARS-CoV-2-IN-67 (Compound 16), a vitamin K derivatives, has anti-SARS-CoV-2 activity (EC50: 64.8 μM in VeroE6/TMPRSS2 cells). SARS-CoV-2-IN-67 inhibits SARS-CoV-2 RdRp activity.
    SARS-CoV-2-IN-67
  • HY-157028
    Antiparasitic agent-19 3032412-28-2 98%
    Antiparasitic agent-19 (compound 40) is a compound with broad-spectrum antiparasitic activity. Antiparasitic agent-19 has minimal toxicity against Trypanosoma brucei, Leishmania Infantum, and Trypanosoma cruzi.
    Antiparasitic agent-19
  • HY-157045
    ATP Synthesis-IN-1 98%
    ATP Synthesis-IN-1 (Compound 4), quinoline derivative, is a potent inhibitor of PA ATP synthesis activity. ATP Synthesis-IN-1 has PA ATP synthesis inhibition with IC50 value of 11.1μg/mL. ATP Synthesis-IN-1 also has antibacterial activity. ATP Synthesis-IN-1 can be used for the research of drug-resistant PA infection.
    ATP Synthesis-IN-1
  • HY-157046
    ATP Synthesis-IN-2 98%
    ATP Synthesis-IN-2 (Compound 5) is an antibacterial compound. ATP Synthesis-IN-2 is a potent ATP synthesis activity inhibitor with IC50 against Pseudomonas aeruginosa (PA) Value of 0.7 μg/mL.
    ATP Synthesis-IN-2
  • HY-157082
    ZHSI-1 2925912-67-8 98%
    ZHSI-1 is an EV71 (Enterovirus 71) inhibitor that inhibits EV71/CVA16 replication and virus-induced pyroptosis associated with viral pathogenesis. ZHSI-1 effectively prevents EV71 infection in neonatal and young mice in animal models. ZHSI-1 can be used to study viral infections such as hand, foot and mouth disease (HFMD).
    ZHSI-1
  • HY-157130
    T3SS-IN-3 98%
    T3SS-IN-3 (compound F-24) is an inhibitor of type III secretion system (T3SS). T3SS-IN-3 inhibits the transcription of hrpY gene significantly without inhibiting bacterial growth.
    T3SS-IN-3
  • HY-157141
    Antibacterial agent 163 16588-39-9 98%
    Antibacterial agent 163 (compound 1), a hydroxyquinoline derivative, is a potent bacterial inhibitor. Antibacterial agent 163 inhibits methicillin-resistant Staphylococcus aureus (MRSA).
    Antibacterial agent 163
  • HY-157142
    Antibacterial agent 165 98%
    Antibacterial agent 165 (compound 3), a hydroxyquinoline derivative, is a potent bacterial inhibitor. Antibacterial agent 165 inhibits methicillin-resistant Staphylococcus aureus (MRSA).
    Antibacterial agent 165
  • HY-157143
    Antibacterial agent 164 98%
    Antibacterial agent 164 (compound 2a) is an antibacterial and antibiofilm agent. Antibacterial agent 164 inhibits S. aureus and B. subtilis (MIC of 0.09 mM), and also exhibits strong anti-B. Subtilis biofilm formation.
    Antibacterial agent 164
  • HY-157144
    SARS-CoV-2-IN-68 2682897-84-1 98%
    SARS-CoV-2-IN-68 (compound 6C) is a covalent SARS-CoV-2 PLpro/Mpro inhibitor with potent antiviral activities. SARS-CoV-2-IN-68 binds to Zn-finger domain of PLpro.
    SARS-CoV-2-IN-68
  • HY-157145
    SARS-CoV-2-IN-69 78471-90-6 98%
    SARS-CoV-2-IN-69 (Compound 7E) is a non-covalent SARS-CoV-2 inhibitor with an EC50 value of 7.4 μM. SARS-CoV-2-IN-69 is a potent inhibitor of SARS-CoV-2 main protease (Mpro) and a non-covalent inhibitor of papain (PLpro).
    SARS-CoV-2-IN-69
  • HY-157260
    Propylbenzene-(CH2)2-COOH 1057602-98-8 98%
    Propylbenzene-(CH2)2-COOH (2c) is a hapten with high titer and inhibition ratio.
    Propylbenzene-(CH2)2-COOH
  • HY-157262
    Methyl isonicotinate-(CH2)2-COOH 2710224-09-0 98%
    Methyl isonicotinate-(CH2)2-COOH (hapten 2b) is a hapten that can be activated with NHS and DCC. Methyl isonicotinate-(CH2)2-COOH has more immunogenicity and hydrophobicity.
    Methyl isonicotinate-(CH2)2-COOH
Cat. No. Product Name / Synonyms Application Reactivity