2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19567R
    PK 11195 (Standard) 85532-75-8 98%
    PK 11195 (Standard) is the analytical standard of PK 11195. This product is intended for research and analytical applications. PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), which targets Leishmania chemotherapy, with IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively.
    PK 11195 (Standard)
  • HY-19581R
    Baquiloprim (Standard) 102280-35-3
    Baquiloprim (Standard) is the analytical standard of Baquiloprim. This product is intended for research and analytical applications. Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria.
    Baquiloprim (Standard)
  • HY-19594R
    Teclozan (Standard) 5560-78-1 98%
    Teclozan (Standard) is the analytical standard of Teclozan. This product is intended for research and analytical applications. Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti-G. intestinalis. Teclozan can be used for the research of protozoan infections.
    Teclozan (Standard)
  • HY-19688A
    Sitamaquine hydrochloride 5330-29-0 98%
    Sitamaquine (WR6026) hydrochloride, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine hydrochloride inhibits mitochondrial complex II (succinate dehydrogenase). Sitamaquine hydrochloride is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes.
    Sitamaquine hydrochloride
  • HY-19951A
    A-867191 hydrochloride 162763-53-3 98%
    A-867191 hydrochloride is a 2-pyridone DNA gyrase inhibitor. A-867191 hydrochloride has antibacterial activity. A-867191 hydrochloride can be used for research on infections.
    A-867191 hydrochloride
  • HY-19952R
    Pleconaril (Standard) 153168-05-9 98%
    Pleconaril (Standard) is the analytical standard of Pleconaril. This product is intended for research and analytical applications. Pleconaril is a picornavirus capsid binding inhibitor that prevents attachment and/or virus uncoating. Pleconaril has potential for use in rhinoviruses and enteroviruses research.
    Pleconaril (Standard)
  • HY-202273
    Capreomycin IA 37280-35-6
    Capreomycin IA is a bactericidal agent targeting bacterial ribosomes, with activity limited primarily to mycobacteria. Capreomycin IA blocks translocation of peptidyl-transfer RNA from the A to the P site to inhibit protein synthesis. Capreomycin IA exerts activity against Mycobacterium tuberculosis. Capreomycin IA can be used for the research of tuberculosis.
    Capreomycin IA
  • HY-208145
    CHIKV-IN-6 1609009-17-7
    CHIKV-IN-6 is a selective CHIKV inhibitor with no cytotoxicity to mammalian cells. CHIKV-IN-6 inhibits CHIKV replication and exhibits little to no activity against other Togaviridae family members. CHIKV-IN-6 can be used for the research of chikungunya virus infection.
    CHIKV-IN-6
  • HY-24470B
    1-(9H-Fluoren-9-yl)ethanol 3023-49-2 98%
    1-(9H-Fluoren-9-yl)ethanol is a prominent fragment in β-lactam antibiotic modification and an important building block for anti-inflammatory agent.
    1-(9H-Fluoren-9-yl)ethanol
  • HY-30220R
    (S)-2-Hydroxy-3-phenylpropanoic acid (Standard) 20312-36-1 98%
    (S)-2-Hydroxy-3-phenylpropanoic acid (Standard) is the analytical standard of (S)-2-Hydroxy-3-phenylpropanoic acid. This product is intended for research and analytical applications. (S)-2-Hydroxy-3-phenylpropanoic acid is the L-configuration of 2-Hydroxy-3-phenylpropanoic acid, and its level is closely related to some diseases, such as phenylketonuria.
    (S)-2-Hydroxy-3-phenylpropanoic acid (Standard)
  • HY-402733
    Antibacterial agent 300 96800-70-3
    Antibacterial agent 300 ((S)-3-[4-(Methylthio)phenyl]-2-oxo-5-(aminomethyl)-oxazolidine) is an aminomethyl oxooxazolidinyl benzene derivative, with antibacterial activity.
    Antibacterial agent 300
  • HY-40284A
    3-Piperidinopropiophenone hydrochloride 886-06-6 98%
    3-Piperidinopropiophenone (hydrochloride) (Compound 2) is a mono Mannich base derived from acetophenone and has antifungal activity.
    3-Piperidinopropiophenone hydrochloride
  • HY-41404R
    Piperonylic acid (Standard) 94-53-1 98%
    Piperonylic acid (Standard) is the analytical standard of Piperonylic acid. This product is intended for research and analytical applications. Piperonylic acid is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic Acid is a selective, mechanism-based inactivator of the trans-cinnamate 4-Hydroxylase. Piperonylic acid has anticancer, antioxidant and antibacterial activities.
    Piperonylic acid (Standard)
  • HY-50730R
    Asparagusic acid (Standard) 2224-02-4
    Asparagusic acid (Standard) is the analytical standard of Asparagusic acid. This product is intended for research and analytical applications. Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor.
    Asparagusic acid (Standard)
  • HY-75800R
    Lomibuvir (Standard) 1026785-55-6 98%
    Lomibuvir (Standard) is the analytical standard of Lomibuvir. This product is intended for research and analytical applications. Lomibuvir (VX-222), a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo-initiated RNA synthesis.
    Lomibuvir (Standard)
  • HY-76204S
    Glycine ethyl ester-13C hydrochloride 58420-91-0 98%
    Glycine ethyl ester-13C hydrochloride is a 13C-labeled Glycine ethyl ester hydrochloride (HY-76204). Glycine ethyl ester monohydrochloride is a Glycine (HY-Y0966) derivative.
    Glycine ethyl ester-13C hydrochloride
  • HY-76228R
    1H-pyrazole (Standard) 288-13-1
    1H-pyrazole (Standard) is the analytical standard of 1H-pyrazole. This product is intended for research and analytical applications. 1H-pyrazole (Pyrazole) is a five-membered heterocyclic compound, and its derivatives are orally effective antimalarial and antileishmanial agents with the potential to modulate targets such as alcohol dehydrogenase and NMDA receptors. 1H-pyrazole derivatives exhibit inhibitory effects on Plasmodium berghei in infected mice and on promastigotes of Leishmania aethiopica, respectively. 1H-pyrazole can be used in research related to malaria and leishmaniasis.
    1H-pyrazole (Standard)
  • HY-76260R
    Faropenem sodium (Standard) 122547-49-3 98%
    Faropenem sodium (Standard) is the analytical standard of Faropenem sodium. This product is intended for research and analytical applications. Faropenem sodium is an orally bioavailable penem antibiotic which can efficiently kill Mycobacterium tuberculosis.
    Faropenem sodium (Standard)
  • HY-76691R
    D-Ribonolactone (Standard) 5336-08-3
    D-Ribonolactone (Standard) is the analytical standard of D-Ribonolactone. This product is intended for research and analytical applications. D-Ribonolactone is sugar lactone and an inhibitor of β-galactosidase of Escherichia coli with a Ki of 26 mM.
    D-Ribonolactone (Standard)
  • HY-77036R
    Furagin (Standard) 1672-88-4 98%
    Furagin (Standard) is the analytical standard of Furagin. This product is intended for research and analytical applications. Furagin (Furazidine) is an analogue of Nitrofurantoin (HY-A0090) and has antibacterial activity. Furagin also inhibits human carbonic anhydrases (Kis: 260 and 57 nM for hCA IX and XII, respectively).
    Furagin (Standard)
Cat. No. Product Name / Synonyms Application Reactivity