CHIKV-IN-6
Based on 1 Customer Validation
CHIKV-IN-6 is a selective CHIKV inhibitor with no cytotoxicity to mammalian cells. CHIKV-IN-6 inhibits CHIKV replication and exhibits little to no activity against other Togaviridae family members. CHIKV-IN-6 can be used for the research of chikungunya virus infection.
For research use only. We do not sell to patients.
- Purity: 99.23%
- CAS No.: 1609009-17-7
- Formula: C15H17N5O2
- Molecular Weight:299.33
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
CHIKV-IN-6 (compound 15b) (7 days post-infection) potently inhibits CHIKV (strain 899) replication in Vero cells with an EC50 of 3 μM and shows no cytotoxicity up to 668 μM[1].
CHIKV-IN-6 (2 days post-infection) potently inhibits replication of multiple CHIKV laboratory strains and clinical isolates in Vero E6 cells, with EC50 values ranging from 0.75 μM to 2.9 μM, and shows no cytotoxicity up to 300 μM[1].
CHIKV-IN-6 (7 days post-infection) shows only marginal antiviral activity against Sindbis virus (HRsp strain) and Semliki Forest virus in Vero cells, with EC50 values of 69 μM and 219 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1609009-17-7
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Appearance Solid
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Molecular Weight 299.33
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Formula C15H17N5O2
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Color White to off-white
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SMILES
O=C1C(N=NN2C3=CC=CC(OC(C)C)=C3)=C2N=C(CC)N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (334.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3408 mL | 16.7040 mL | 33.4079 mL | 83.5199 mL |
| 5 mM | 0.6682 mL | 3.3408 mL | 6.6816 mL | 16.7040 mL | |
| 10 mM | 0.3341 mL | 1.6704 mL | 3.3408 mL | 8.3520 mL | |
| 15 mM | 0.2227 mL | 1.1136 mL | 2.2272 mL | 5.5680 mL | |
| 20 mM | 0.1670 mL | 0.8352 mL | 1.6704 mL | 4.1760 mL | |
| 25 mM | 0.1336 mL | 0.6682 mL | 1.3363 mL | 3.3408 mL | |
| 30 mM | 0.1114 mL | 0.5568 mL | 1.1136 mL | 2.7840 mL | |
| 40 mM | 0.0835 mL | 0.4176 mL | 0.8352 mL | 2.0880 mL | |
| 50 mM | 0.0668 mL | 0.3341 mL | 0.6682 mL | 1.6704 mL | |
| 60 mM | 0.0557 mL | 0.2784 mL | 0.5568 mL | 1.3920 mL | |
| 80 mM | 0.0418 mL | 0.2088 mL | 0.4176 mL | 1.0440 mL | |
| 100 mM | 0.0334 mL | 0.1670 mL | 0.3341 mL | 0.8352 mL |
CHIKV-IN-6 Related Classifications
HY-208145 Related Classifications
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