CHIKV-IN-6
Based on 1 Customer Validation
CHIKV-IN-6 is a selective CHIKV inhibitor with no cytotoxicity to mammalian cells. CHIKV-IN-6 inhibits CHIKV replication and exhibits little to no activity against other Togaviridae family members. CHIKV-IN-6 can be used for the research of chikungunya virus infection.
For research use only. We do not sell to patients.
- Purity: 99.23%
- CAS No.: 1609009-17-7
- Formula: C15H17N5O2
- Molecular Weight:299.33
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
CHIKV-IN-6 (compound 15b) (7 days post-infection) potently inhibits CHIKV (strain 899) replication in Vero cells with an EC50 of 3 μM and shows no cytotoxicity up to 668 μM[1].
CHIKV-IN-6 (2 days post-infection) potently inhibits replication of multiple CHIKV laboratory strains and clinical isolates in Vero E6 cells, with EC50 values ranging from 0.75 μM to 2.9 μM, and shows no cytotoxicity up to 300 μM[1].
CHIKV-IN-6 (7 days post-infection) shows only marginal antiviral activity against Sindbis virus (HRsp strain) and Semliki Forest virus in Vero cells, with EC50 values of 69 μM and 219 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1609009-17-7
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Appearance Solid
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Molecular Weight 299.33
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Formula C15H17N5O2
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Color White to off-white
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SMILES
O=C1C(N=NN2C3=CC=CC(OC(C)C)=C3)=C2N=C(CC)N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CHIKV-IN-6 Related Classifications
HY-208145 Related Classifications
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