2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N2224R
    Guaijaverin (Standard) 22255-13-6
    Guaijaverin (Standard) is the analytical standard of Guaijaverin. This product is intended for research and analytical applications. Guaijaverin is a urease inhibitor with an IC50 of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities.
    Guaijaverin (Standard)
  • HY-N2230A
    (E/Z)-N-p-trans-Coumaroyltyramine 20375-37-5 98%
    (E/Z)-N-p-trans-Coumaroyltyramine is an amide. (E/Z)-N-p-trans-Coumaroyltyramine is present in the leaves of Annona muricata L. (E/Z)-N-p-trans-Coumaroyltyramine exhibits certain brine shrimp larvicidal activity.
    (E/Z)-N-p-trans-Coumaroyltyramine
  • HY-N2253R
    Neoruscogenin (Standard) 17676-33-4
    Neoruscogenin (Standard) is the analytical standard of Neoruscogenin. This product is intended for research and analytical applications. Neoruscogenin, a member of the steroidal sapogenin family, is a high-affinity agonist of the nuclear receptor RORα (NR1F1) (EC50 = 0.11 μM).
    Neoruscogenin (Standard)
  • HY-N2260R
    Cephaeline dihydrochloride (Standard) 5853-29-2
    Cephaeline (dihydrochloride) (Standard) is the analytical standard of Cephaeline (dihydrochloride). This product is intended for research and analytical applications. Cephaeline dihydrochloride is a selective CYP2D6 inhibtor with an IC50 of 121 μM.
    Cephaeline dihydrochloride (Standard)
  • HY-N2268R
    Gymnemagenin (Standard) 22467-07-8
    Gymnemagenin (Standard) is the analytical standard of Gymnemagenin. This product is intended for research and analytical applications. Gymnemagenin is a triterpenoid isolated from G. sylvestre. Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties.
    Gymnemagenin (Standard)
  • HY-N2297R
    Kaji-ichigoside F1 (Standard) 95298-47-8
    Flunisolide (hemihydrate) (Standard) is the analytical standard of Flunisolide (hemihydrate). This product is intended for research and analytical applications. Flunisolide hemihydrate is a corticosteroid, which is an orally active glucocorticoid receptor activator with anti-inflammatory activity. Flunisolide hemihydrate can induce eosinophil apoptosis, and is used for the research of asthma or rhinitis, and inflammation.
    Kaji-ichigoside F1 (Standard)
  • HY-N2301R
    Pleuromutilin (Standard) 125-65-5 98%
    Pleuromutilin (Standard) is the analytical standard of Pleuromutilin. This product is intended for research and analytical applications. Pleuromutilin (Drosophilin B) inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.
    Pleuromutilin (Standard)
  • HY-N2329R
    Piperlongumine (Standard) 20069-09-4 98%
    Piperlongumine is a alkaloid, possesses ant-inflammatory, antibacterial, antiangiogenic, antioxidant, antitumor, and antidiabetic activities. Piperlongumine induces ROS, and induces apoptosis in cancer cell lines. Piperlongumine shows anti-cardiac fibrosis activity, suppresses myofibroblast transformation via suppression of the ERK1/2 signaling pathway. Piperlongumin could be used in the study of migrasome.
    Piperlongumine (Standard)
  • HY-N2360R
    Hinokiflavone (Standard) 19202-36-9 98%
    Hinokiflavone is a novel modulator of pre-mRNA splicing activity extracted from plants with anti-inflammatory, anti-tumor and antiviral activities. Hinokiflavone is also a potent inhibitor for matrix metalloproteinases (MMPs). Hinokiflavone attenuates the virulence of Methicillin (HY-121544)-resistant staphylococcus aureus by inhibiting caseinolytic protease P (ClpP) with an IC50 value of 34.36 mg/mL. Hinokiflavone induces apoptosis via the reactive oxygen species-mitochondria-mediated apoptotic pathway and inhibits tumor cell migration and invasion. Hinokiflavone is a SUMO protease inhibitor against sentrin-specific protease 1 (SENP1) activity.
    Hinokiflavone (Standard)
  • HY-N2472R
    Medicagenic acid (Standard) 599-07-5
    Medicagenic acid (Standard) is the analytical standard of Medicagenic acid. This product is intended for research and analytical applications. Medicagenic acid (Castanogenin) is isolated from the roots of Herniaria glabra, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes. Medicagenic acid (Castanogenin) has low enzyme inhibitory activities, the target enzymes are xanthine oxidase, collagenase, elastase, tyrosinase, ChE.
    Medicagenic acid (Standard)
  • HY-N2492R
    (E)-Methyl 4-coumarate (Standard) 19367-38-5 99.94%
    (E)-Methyl 4-coumarate (Standard) is the analytical standard of (E)-Methyl 4-coumarate (HY-N2492). This product is intended for research and analytical applications. (E)-Methyl 4-coumarate (Methyl 4-hydroxycinnamate) is a phenolic compound and derivative of Cinnamic acid (HY-N0610A). (E)-Methyl 4-coumarate can be found in several plants, such as the leaves of Allium cepa and Morinda citrifolia L. (E)-Methyl 4-coumarate, when combined with Carnosic acid (HY-N0644), induces Apoptosis. (E)-Methyl 4-coumarate inhibits GSK3β activity and modulates inflammatory cytokine levels (increasing IL-10 and decreasing IL-4). (E)-Methyl 4-coumarate combined with Carnosic acid exhibits anticancer effects against acute myeloid leukemia. (E)-Methyl 4-coumarate ameliorates Plasmodium berghei NK65 infection.
    (E)-Methyl 4-coumarate (Standard)
  • HY-N2493R
    Lawsone (Standard) 83-72-7 98%
    Lawsone is an orally active naphthoquinone dye that can be isolated from the leaves of Lawsonia inermis. Lawsone can induce apoptosis. Lawsone has antibacterial, antitumor and antioxidant activities. Lawsone can be used in anti-tumor drug research.
    Lawsone (Standard)
  • HY-N2512R
    1-Monomyristin (Standard) 589-68-4
    1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans.
    1-Monomyristin (Standard)
  • HY-N2552R
    Vitamin K5 hydrochloride (Standard) 130-24-5
    Vitamin K5 (hydrochloride) (Standard) is the analytical standard of Vitamin K5 (hydrochloride). This product is intended for research and analytical applications. Vitamin K5 hydrochloride is a photosensitizer and a antimicrobial agent. Vitamin K5 hydrochloride is a specific PKM2 inhibitor with IC50 values of 28, 191 and 120 μM for PKM2, PKM1 and PKL. Vitamin K5 hydrochloride induces apoptosis of colon 26 cells. Vitamin K5 hydrochloride can be used for the research of infection and cancer, and it also can be used as a preservative for pharmaceuticals, foods, and beverages[1][2][3].
    Vitamin K5 hydrochloride (Standard)
  • HY-N2590R
    Lupenone (Standard) 1617-70-5 98%
    Lupenone is an orally active lupine-type triterpenoid that can be isolated from Musa basjoo. Lupenone Lupenone plays a role through the PI3K/Akt/mTOR and NF-κB signaling pathways. Lupenone has anti-inflammatory, antiviral, antidiabetic and anticancer activities.
    Lupenone (Standard)
  • HY-N3006R
    Sakuranetin (Standard) 2957-21-3 98%
    Sakuranetin is a cherry flavonoid phytoalexin, shows strong antifungal activity. Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury.
    Sakuranetin (Standard)
  • HY-N3017R
    Artemitin (Standard) 479-90-3 98%
    Artemitin (Standard) is the analytical standard of Artemitin. This product is intended for research and analytical applications. Artemitin is a flavonol found in Laggera pterodonta (DC.) Benth., with antioxidative, anti-inflammatory, and antiviral activity.
    Artemitin (Standard)
  • HY-N3031R
    Grosvenorine (Standard) 156980-60-8
    Grosvenorine (Standard) is the analytical standard of Grosvenorine. This product is intended for research and analytical applications. Grosvenorine is an orally active flavonoid glycoside found in S. grosvenorii. Grosvenorine exhibits antibacterial, antioxidant and antiinflammation activities. Grosvenorine can induce apoptosis and increases anti-apoptotic Bcl-2 protein expression and reduces pro-apoptotic P53 protein expression in gastric tissues. Grosvenorine enhances mucin/glycoprotein secretion, regulates gastric pH, and reduces gastric lesion incidence.Grosvenorine increases glutathione peroxidase, catalase, and SOD levels, reduces lipid peroxidation (MDA), and lowers TNF-α and IL-6 levels. Grosvenorine can be used for the researches of bacterial infection and Gastric ulcer.
    Grosvenorine (Standard)
  • HY-N3056R
    Pinosylvin monomethyl ether (Standard) 35302-70-6
    Pinosylvin monomethyl ether (Standard) is the analytical standard of Pinosylvin monomethyl ether. This product is intended for research and analytical applications. Pinosylvin monomethyl ether has antibacterial effect and fungicidal activity.
    Pinosylvin monomethyl ether (Standard)
  • HY-N3074R
    Hexahydrofarnesyl acetone (Standard) 502-69-2
    alpha-Bisabolol (Standard) is the analytical standard of alpha-Bisabolol. This product is intended for research and analytical applications. alpha-Bisabolol, an orally active sesquiterpene alcohol, induces cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol exerts a protective action against Cisplatin (HY-17394)-induced nephrotoxicity by mitigating inflammation and oxidative stress through the inhibition of NFκB activation. alpha-Bisabolol exhibits anti-inflammatory, analgesic, antibiotic and anticancer activities.
    Hexahydrofarnesyl acetone (Standard)
Cat. No. Product Name / Synonyms Application Reactivity