(E/Z)-N-p-trans-Coumaroyltyramine
(E/Z)-N-p-trans-Coumaroyltyramine is an amide. (E/Z)-N-p-trans-Coumaroyltyramine is present in the leaves of Annona muricata L. (E/Z)-N-p-trans-Coumaroyltyramine exhibits certain brine shrimp larvicidal activity.
For research use only. We do not sell to patients.
- CAS No.: 20375-37-5
- Formula: C17H17NO3
- Molecular Weight:283.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | ED50 |
3.24 μg/mL
Compound: 5
|
Cytotoxicity against human A549 cells after 7 days
Cytotoxicity against human A549 cells after 7 days
|
[PMID: 1593281] |
| A549 | IC50 |
15.21 μg/mL
Compound: 12
|
Cytotoxicity against human A549 cells by MTT assay
Cytotoxicity against human A549 cells by MTT assay
|
[PMID: 22413887] |
| BV-2 | IC50 |
2.2 μM
Compound: 22
|
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess assay
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess assay
|
[PMID: 33822610] |
| Ca9-22 | IC50 |
12.28 μg/mL
Compound: 12
|
Cytotoxicity against human Ca9-22 cells by MTT assay
Cytotoxicity against human Ca9-22 cells by MTT assay
|
[PMID: 22413887] |
| Hep 3B2 | IC50 |
11.23 μg/mL
Compound: 12
|
Cytotoxicity against human Hep3B cells by MTT assay
Cytotoxicity against human Hep3B cells by MTT assay
|
[PMID: 22413887] |
| HepG2 | IC50 |
9.57 μg/mL
Compound: 12
|
Cytotoxicity against human HepG2 cells by MTT assay
Cytotoxicity against human HepG2 cells by MTT assay
|
[PMID: 22413887] |
| HT-29 | ED50 |
0.674 μg/mL
Compound: 5
|
Cytotoxicity against human HT-29 cells after 7 days
Cytotoxicity against human HT-29 cells after 7 days
|
[PMID: 1593281] |
| KB | IC50 |
>47.8 μM
Compound: 14
|
Cytotoxicity against human KB cells by sulforhodamine B assay
Cytotoxicity against human KB cells by sulforhodamine B assay
|
[PMID: 26928423] |
| MCF7 | ED50 |
0.716 μg/mL
Compound: 5
|
Cytotoxicity against human MCF7 cells after 7 days
Cytotoxicity against human MCF7 cells after 7 days
|
[PMID: 1593281] |
| MCF7 | IC50 |
>20 μg/mL
Compound: 12
|
Cytotoxicity against human MCF7 cells by MTT assay
Cytotoxicity against human MCF7 cells by MTT assay
|
[PMID: 22413887] |
| MDA-MB-231 | IC50 |
>20 μg/mL
Compound: 12
|
Cytotoxicity against human MDA-MB-231 cells by MTT assay
Cytotoxicity against human MDA-MB-231 cells by MTT assay
|
[PMID: 22413887] |
| Vero | IC50 |
>47.8 μM
Compound: 14
|
Cytotoxicity against African green monkey Vero cells by sulforhodamine B assay
Cytotoxicity against African green monkey Vero cells by sulforhodamine B assay
|
[PMID: 26928423] |
In Vitro
(E/Z)-N-p-trans-Coumaroyltyramine can be isolated from the leaves of Annona muricata using sequential solvent extraction and chromatographic purification steps[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 20375-37-5
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Molecular Weight 283.33
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Formula C17H17NO3
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SMILES
O=C(C=CC1=CC=C(O)C=C1)NCCC2=CC=C(O)C=C2
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)