Annonaceae

Uvaria grandiflora Roxb. (5)
Fissistigma polyanthum (Hook. f. et Thoms.) Merr. (3)
Goniothalamus amuyon (Bl.) Merr. (3)
Annona montana Macf. (2)
Fissistigma glaucescens (2)
Fissistigma oldhamii (Hemsl.) Merr. (2)
Annona muricata Linn. (2)
Annona cherimola Mill. (1)
Annona crassiflora Mart. (1)
Annona glabra Linn. (1)
Artabotrys maingayi Hook.f. & Thomson (1)
Cananga odorata (1)
Cleistochlamys kirkii Oliver (1)
Dasymaschalon rostratum Merr. et Chun (1)
Fissistigma balansae (A. DC.) Merr. (1)
Fissistigma poilanei (Ast) Tsiang et P. T. Li (1)
Goniothalamus calvicarpus Craib (1)
Goniothalamus cardiopetalus (Dalzell) Hook.f. & Thomson (1)

Goniothalamus tapis Miq. (1)

Melodorum fruticosum Lour. (1)

Melodorum siamensis (1)

Miliusa sinensis Finet et Gagnep. (1)

Polyalthia cinnamomea (1)

Polyalthia nemoralis A. DC. (1)

Unonopsis duckei R.E.Fr. (1)

Uvaria tonkinensis Finet et Gagnep. (1)

Annonaceae (38):

Cat. No. Product Name CAS No. Purity Chemical Structure

HY-N8241

N-trans-Caffeoyltyramine 103188-48-3 99.71%

N-TRANS-CaffeoyLtyramine is an effective inflammatory response regulator, which has antioxidant activity and anticoagulation effects.

HY-N0649

Narcissin 604-80-8 99.72%

Narcissin (Narcissoside), a flavonol glycoside, exhibits evident scavenging activity against both authentic ONOO^- and SIN-1-derived ONOO^- with IC₅₀s of 3.5 and 9.6 μM, respectively.

HY-B0935

Benzyl benzoate 120-51-4 ≥98.0%

Benzyl benzoate (Phenylmethyl benzoate) is an orally active anti-scabies agent, acaricide (EC₅₀= 0.06 g/m²) and fungicide. Benzyl benzoate is an angiotensin II (Ang II) inhibitor with antihypertensive effects. Benzyl benzoate can be used in perfumes, pharmaceuticals and the food industry.

HY-N7203

N-Caffeoyl O-methyltyramine 189307-47-9 98.37%

N-Caffeoyl O-methyltyramine is a class of alkaloid isolated from Cuscuta reflexa with strong inhibitory activity against α-glucosidase (IC₅₀ of 103.58 μM).

HY-126066

(-)-Syringaresinol 6216-81-5 99.95%

(-)-Syringaresinol, found in stems of Annona Montana, possesses anti-cancer activity.

HY-116590

Glaziovine 17127-48-9

Glaziovine, a proaporphine alkaloid, has anxiolytic activity. Glaziovine can be used for neuropharmacological research.

HY-N12075

Dehydrodiscretamine chloride 78134-82-4

Dehydrodiscretamine chloride is a dual inhibitor of AChE and BChE with IC₅₀s of 17.8 and 118.8 μM, respectively. Dehydrodiscretamine chloride has antioxidant activity. Dehydrodiscretamine chloride can be used in study Alzheimer’s disease.

HY-122989

Aristolactam BIII 53948-10-0

Aristolactam BIII is a potent DYRK1A inhibitor and inhibits the kinase activity of DYRK1A in vitro (IC₅₀= 9.67 nM. Aristolactam BIII rescues the proliferative defects of DYRK1A transgenic (TG) mouse-derived fibroblasts and neurological and phenotypic defects of DS-like Drosophila models.

HY-N6805

Isoeugenol acetate 93-29-8 98.92%

Isoeugenol acetate (Acetyl isoeugenol), an essential oil constituent of nutmeg, clove, and cinnamon, shows excellent inhibitory effects against some metabolic enzymes such as acetylcholinesterase (AChE) enzymes (IC₅₀=77 nM; K_i=16 nM), α-glycosidase (IC₅₀=19.25 nM; K_i=21 nM), and α-amylase (IC₅₀=411.5 nM). Isoeugenol acetate is used medical and cosmetics industries for its antioxidant, anticancer, antimicrobial and anti-inflammatory properties.

HY-N2318

Podocarpic acid 5947-49-9 99.78%

Podocarpic acid is a natural product, which has the best all-round positive effect and acts as a novel TRPA1 activator.

HY-N2877

Annonacin 111035-65-5

Annonacin is an Acetogenin and promotes cytotoxicity via a pathway inhibiting the mitochondrial complex. Annonacin is the active agent found in Annona muricata to act as an inhibitor of sodium/potassium (NKA) and sarcoplasmic reticulum (SERCA) ATPase pumps.

HY-N9499

3-Methoxyflavone 7245-02-5 99.88%

3-Methoxyflavone is a flavonoid compound isolated from Artemisia incanescens with antiviral activity.

HY-N2051

Zeylenone 193410-84-3 ≥98.0%

Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways.

HY-N7227

Anonaine 1862-41-5

Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor.

HY-N7450

Icariside D2 38954-02-8 ≥98.0%

Icariside D2, isolated from Annona glabra fruit, inhibits angiotensin-converting enzyme. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC₅₀ value of 9.0 ± 1.0 μM. Icariside D2 induces apoptosis .

HY-119398

Lanuginosine 23740-25-2

Lanuginosine (Compound 12) is an AChE inhibitor (IC₅₀: 10.9 μM). Lanuginosine inhibits Aβ aggregation. Lanuginosine can be used for research of Alzheimer’s disease.

HY-122930

Lysicamine 15444-20-9

Lysicamine, a natural compound, possesses antibacterial, anticancer and anti-inflammation activity.

HY-N10391

(-)-Cleistenolide 1003600-48-3

(-)-Cleistenolide is a α,β-unsaturated δ-lactone isolated from Cleistochlamys kirkii Oliver. (-)-Cleistenolide has antibacterial and antitumor activity.

HY-N10606

Uvagrandol

Uvagrandol potently inhibits α-glucosidase and porcine lipase (IC₅₀: 15.2 μM, 11.2 μM respectively). Uvagrandol can be used in the research of Type 2 diabetes and obesity.

HY-N12027

AChE/BChE-IN-14

AChE/BChE-IN-14 (compound 13) is a benzylisoquinoline alkaloid isolated from the roots of Fissistigma polyanthum. AChE/BChE-IN-14 exhibits AChE and BChE inhibitions with antioxidant activities. AChE/BChE-IN-14 can be used for Alzheimer’s disease research.

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