2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Potassium Channel Sodium Channel Na+/K+ ATPase Calcium Channel
  4. Annonacin

Annonacin is an Acetogenin and promotes cytotoxicity via a pathway inhibiting the mitochondrial complex. Annonacin is the active agent found in Annona muricata to act as an inhibitor of sodium/potassium (NKA) and sarcoplasmic reticulum (SERCA) ATPase pumps.

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Annonacin Chemical Structure

Annonacin Chemical Structure

CAS No. : 111035-65-5

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Based on 1 publication(s) in Google Scholar

Annonacin Related Antibodies

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Description

Annonacin is an Acetogenin and promotes cytotoxicity via a pathway inhibiting the mitochondrial complex. Annonacin is the active agent found in Annona muricata to act as an inhibitor of sodium/potassium (NKA) and sarcoplasmic reticulum (SERCA) ATPase pumps[1].

Molecular Weight

596.88

Formula

C35H64O7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1O[C@@H](C)C=C1C[C@H](O)CCCCC[C@@H](O)CCCC[C@@H](O)[C@@H]2O[C@@H]([C@H](O)CCCCCCCCCCCC)CC2
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Purity: ≥97.0%

COA (241 KB) HNMR (189 KB)

Handling Instructions (2659 KB)
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Annonacin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Annonacin111035-65-5Potassium ChannelSodium ChannelNa+/K+ ATPaseCalcium ChannelKcsANa channelsNa+ channelsSodium potassium pumpCa2+ channelsCa channelsAcetogenincytotoxicitymitochondrialsodiumpotassiumsarcoplasmicreticulumATPaseInhibitorinhibitorinhibit

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