2. Infection

Infection

Infection

Related Products

PDF 70.44 MB

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-103658R
    Myramistin (Standard) 15809-19-5 98%
    Myramistin (Standard) is the analytical standard of Myramistin (HY-103658). This product is intended for research and analytical applications. Myramistin (Miramistin) is an antibacterial agent targeting bacterial cell membrane. Myramistin can bind to the negatively charged surface of bacteria through its cationic properties, disrupt the integrity of the bacterial cell membrane, inhibit bacterial metabolism and growth, and induce cell death, thus exerting antibacterial activity.
    Myramistin (Standard)
  • HY-10367AR
    Canertinib dihydrochloride (Standard) 289499-45-2 98%
    Canertinib (dihydrochloride) (Standard) is the analytical standard of Canertinib (dihydrochloride). This product is intended for research and analytical applications. Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. Canertinib dihydrochloride is active against vaccinia virus respiratory infection in mice.
    Canertinib dihydrochloride (Standard)
  • HY-104012R
    Islatravir (Standard) 865363-93-5 98%
    Islatravir (Standard) is the analytical standard of Islatravir (HY-104012). This product is intended for research and analytical applications. Islatravir (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. Islatravir is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Islatravir (Standard)
  • HY-104029R
    Olorofim (Standard) 1928707-56-5 98%
    Olorofim (Standard) is the analytical standard of Olorofim (HY-104029). This product is intended for research and analytical applications. Olorofim (F901318) selectively inhibits fungal dihydroorotate dehydrogenase (DHODH), a key enzyme in the pyrimidine biosynthesis pathway. Olorofim (F901318). Olorofim exhibits excellent activity against A. fumigatus and other Aspergillus spp..
    Olorofim (Standard)
  • HY-104032R
    Ac-CoA Synthase-IN-1 (Standard) 508186-14-9
    Ac-CoA Synthase-IN-1 (Standard) is the analytical standard of Ac-CoA Synthase-IN-1 (HY-104032). This product is intended for research and analytical applications. Ac-CoA Synthase-IN-1 is a potent, reversible acetate-dependent acetyl-CoA synthetase 2 (ACSS2) inhibitor with an IC50 of 0.6 μM. Ac-CoA Synthase-IN-1 inhibits the respiratory syncytial virus (RSV).
    Ac-CoA Synthase-IN-1 (Standard)
  • HY-104074R
    Pocapavir (Standard) 146949-21-5 98%
    Pocapavir (Standard) is the analytical standard of Pocapavir (HY-104074). This product is intended for research and analytical applications. Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections.
    Pocapavir (Standard)
  • HY-10466S1
    Daclatasvir-13C2,d6 98%
    Daclatasvir-13C2,d6 (BMS-790052-13C2,d6) is 13C and deuterium labeled Daclatasvir. Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 μM and 3.27 μM, respectively.
    Daclatasvir-13C2,d6
  • HY-105033R
    Irloxacin (Standard) 91524-15-1 98%
    Irloxacin (Standard) is the analytical standard of Irloxacin (HY-105033). This product is intended for research and analytical applications. Irloxacin (Pirfloxacin) is a quinolone antibacterial agent. Irloxacin shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. Orally active.
    Irloxacin (Standard)
  • HY-105048A
    Omiganan pentahydrochloride 269062-93-3 98%
    Omiganan pentahydrochloride is a cationic peptide compound with a broad antibacterial profile. Omiganan pentahydrochloride is capable of inhibiting a variety of bacteria, including yeast, and is active against both gram-positive and gram-negative bacteria. Omiganan pentahydrochloride is able to interact with the bacterial cell membrane, causing the destruction of the cell membrane and the death of the bacteria. Omiganan pentahydrochloride can be used for the study of antimicrobial activity against pathogens commonly associated with catheter-associated infections, including strains with drug-resistant phenotypes.
    Omiganan pentahydrochloride
  • HY-105117R
    Fantofarone (Standard) 114432-13-2 98%
    Fantofarone (Standard) is the analytical standard of Fantofarone. This product is intended for research and analytical applications. Fantofarone is a highly potent Calcium Channel antagonist.
    Fantofarone (Standard)
  • HY-105180A
    Lenapenem hydrochloride hydrate 149882-71-3 98%
    Lenapenem (BO-2727) hydrochloride hydrate, a carbapenem antibiotic, has potent antibacterial activity against Gram-positive and Gram-negative bacteria including P. aeruginosa.
    Lenapenem hydrochloride hydrate
  • HY-105268R
    AzddMeC (Standard) 87190-79-2 98%
    AzddMeC (Standard) is the analytical standard of AzddMeC (HY-105268). This product is intended for research and analytical applications. AzddMeC (CS-92) is an antiviral nucleoside analogue and a potent potent, selective and orally active HIV-1 reverse transcriptase and HIV-1 replication inhibitor. In HIV-1-infected human PBM cells and HIV-1-infected human macrophages, the EC50 values of AzddMeC are 9 nM and 6 nM, respectively. AzddMeC is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    AzddMeC (Standard)
  • HY-10545AR
    Taribavirin hydrochloride (Standard) 40372-00-7 98%
    Taribavirin hydrochloride (Standard) is the analytical standard of Taribavirin hydrochloride (HY-10545A). This product is intended for research and analytical applications. Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia.
    Taribavirin hydrochloride (Standard)
  • HY-105656R
    Hydrocortisone phosphate sodium (Standard) 6000-74-4 98%
    Hydrocortisone phosphate sodium (Standard) is the analytical standard of Hydrocortisone phosphate sodium (HY-105656). This product is intended for research and analytical applications. Hydrocortisone phosphate sodium is a soft steroid with low anti-inflammatory properties and a short duration of action. Hydrocortisone phosphate sodium can be used for the research for several ocular conditions and gastric ulcers.
    Hydrocortisone phosphate sodium (Standard)
  • HY-10570S2
    Nevirapine-d8 1051418-86-0 98%
    Nevirapine-d8 (BI-RG 587-d8) is deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM.
    Nevirapine-d8
  • HY-10570S3
    Nevirapine-d5 1189717-29-0 98%
    Nevirapine-d5 (BI-RG 587-d5) is deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM.
    Nevirapine-d5
  • HY-10571AR
    Delavirdine mesylate (Standard) 147221-93-0 98%
    Delavirdine (mesylate) (Standard) is the analytical standard of Delavirdine (mesylate). This product is intended for research and analytical applications. Delavirdine (U 90152) mesylate is a potent, highly specific and orally active non-nucleoside reverse transcriptase inhibitor (NNRTI). Delavirdine mesylate selectively inhibits HIV-1 reverse transcriptase (RT) (IC50=0.26?μM) over DNA polymerase?α?(IC50=440 μM) and polymerase?δ (IC50>550?μM). Delavirdine mesylate is an inhibitor of HIV-1 replication and can can be used for the study of AIDs.
    Delavirdine mesylate (Standard)
  • HY-10572BS
    (Rac)-Efavirenz-d4 1246812-58-7 98%
    (Rac)-Efavirenz-d4 is a labelled racemic Efavirenz. Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture. (Rac)-Efavirenz-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    (Rac)-Efavirenz-d4
  • HY-10574S1
    Rilpivirine-13C6 98%
    Rilpivirine-13C6 (R278474-13C6) is 13C labeled Rilpivirine. Rilpivirine (R278474) is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM). Rilpivirine has a high genetic barrier to resistance development of HIV.
    Rilpivirine-13C6
  • HY-10581CR
    Gatifloxacin sesquihydrate (Standard) 180200-66-2
    Gatifloxacin (sesquihydrate) (Standard) is the analytical standard of Gatifloxacin (sesquihydrate). This product is intended for research and analytical applications. Gatifloxacin sesquihydrate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin sesquihydrate inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin sesquihydrate can be used to treat bacterial conjunctivitis?in vivo.
    Gatifloxacin sesquihydrate (Standard)
Cat. No. Product Name / Synonyms Application Reactivity