2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W841708
    5-((1H-Indol-3-yl)methylene)imidazolidine-2,4-dione 5453-51-0
    5-((1H-Indol-3-yl)methylene)imidazolidine-2,4-dione is an inhibitor of dengue virus NS2B-NS3 protease and thrombin. 5-((1H-Indol-3-yl)methylene)imidazolidine-2,4-dione can be used in the research of infectious diseases.
    5-((1H-Indol-3-yl)methylene)imidazolidine-2,4-dione
  • HY-W844796
    2-Amino-5-methyl-5-hexenoic acid 73322-75-5 98%
    2-Amino-5-methyl-5-hexenoic acid ((S)-2-Amino-5-methylhex-5-enoic acid) is a Methionine analog that competes with methionine and resulting in inhibition of cell growth. 2-Amino-5-methyl-5-hexenoic acid inhibits protein synthesis but not DNA or RNA synthesis in S. typhimurium TA1535 and E. coli K-12. X
    2-Amino-5-methyl-5-hexenoic acid
  • HY-W854341
    Chitotriose 41708-93-4 98%
    Chitotriose is a chitooligosaccharide that can be isolated from crab shell chitosan. Chitotriose has antibacterial effect against salmonella.
    Chitotriose
  • HY-W856920
    Parvaquone 4042-30-2
    Parvaquone is an antiparasite agent with an in vitro ED50 of 0.006 mg/L. Parvaquone reduces the proportion of Theileria parva schizont-infected cells. Parvaquone can be used for the research of east coast fever (Theileria parva infection).
    Parvaquone
  • HY-W895978
    Isoconazole 27523-40-6
    Isoconazole is an antifungal agent against Candida albicans. Isoconazole is a broad-spectrum antimicrobial azole that can be studied in research on dermatomycoses.
    Isoconazole
  • HY-W904855
    Apicidin D2 177562-78-6
    Apicidin D2 (Compound 4), a fungal metabolite, is a Accessory gene regulator A (AgrA) quorum-sensing inhibitor. Apicidin D2 has anti-virulence activity. Apicidin D2 suppresses MRSA agr activation and shows potent inhibitory activities against all agr types in a nonbiocidal manner. Apicidin D2 can be used for MRSA infections research.
    Apicidin D2
  • HY-W928617
    Spectinomycin sulfate hydrate 64058-48-6 98%
    Spectinomycin sulfate hydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin sulfate hydrate acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin sulfate hydrate is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM-.
    Spectinomycin sulfate hydrate
  • HY-W928623
    2-Acetylthiophene thiosemicarbazone 5351-71-3 98%
    2-Acetylthiophene thiosemicarbazone is an antibacterial agent. 2-Acetylthiophene thiosemicarbazone exhibits anticancer activity, with an IC50 value of 8.6 μM against HT-29 cells.
    2-Acetylthiophene thiosemicarbazone
  • HY-W983371
    10(R)-Hydroxystearic acid 5856-32-6
    10(R)-Hydroxystearic acid is a derivative of Oleic acid (HY-N1446). 10(R)-Hydroxystearic acid can be biocatalytically produced by Lactobacillus rhamnosus ATCC 53103.
    10(R)-Hydroxystearic acid
  • HY-W983893
    7-Hydroxytropolone 34777-04-3 98%
    7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic with anti-Gram-positive bacteria, negative bacteria, yeast and fungi activity, and has the effect of inhibiting 2''-O-Adenylyltransferase.
    7-Hydroxytropolone
  • HY-W984166
    Antibiotic U 44590 57350-36-4 98%
    5,6-Dihydro-5-azathymidine has anti-Gram-positive bacteria, negative bacteria and DNA virus activities.
    Antibiotic U 44590
  • HY-W995025
    Actinobolin 24397-89-5 98%
    Actinobolin ((+)-Actinobolin) is an antibiotic, that inhibits protein synthesis by targeting bacterial and eukaryotic ribosomes. Actinobolin inhibits Mycobacterium smegmatis, Escherichia coli and rabbit reticulocyte lysate (RRL) with an IC50 of 19.2, 27.9, and 288 μmol/L, respectively.
    Actinobolin
  • HY-100029AR
    Bay 41-4109 racemate (Standard) 298708-79-9 98%
    Bay 41-4109 (racemate) (Standard) is the analytical standard of Bay 41-4109 (racemate). This product is intended for research and analytical applications. BAY 41-4109 racemate is the racemate of BAY 41-4109. BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
    Bay 41-4109 racemate (Standard)
  • HY-100313AR
    YM-53601 (Standard) 182959-33-7 98%
    YM-53601 (Standard) is the analytical standard of YM-53601 (HY-100313A). This product is intended for research and analytical applications. YM-53601, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo. YM-53601 inhibits squalene synthase derived from human hepatoma cells with an IC50 of 79 nM. Lipid-lowering agent. YM-53601 is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and abrogates HCV propagation.
    YM-53601 (Standard)
  • HY-100540BR
    Golgicide A-2 (Standard) 1394285-50-7 98%
    Golgicide A-2 (Standard) is the analytical standard of Golgicide A-2 (HY-100540B). This product is intended for research and analytical applications. Golgicide A-2 (GCA-2), a Golgicide A (GCA) derivative, is the most active enantiomer of GCA. Golgicide A-2 displays high selectivity and efficiency in killing An. stephensi larvae and can be used for the research of dengue virus related diseases.
    Golgicide A-2 (Standard)
  • HY-100540CR
    Golgicide A-1 (Standard) 1394285-49-4 98%
    Golgicide A-1 (Standard) is the analytical standard of Golgicide A-1 (HY-100540C). This product is intended for research and analytical applications. Golgicide A-1 (GCA-1) is a less active cis-diastereomer of Golgicide A (GCA). Golgicide A-1 weakly inhibits mosquito reproduction.
    Golgicide A-1 (Standard)
  • HY-101064S4
    Fmoc-leucine-15N 200937-57-1 98.5%
    Fmoc-leucine-15N is a 15N-labeled and 15N-labled Fmoc-leucine (HY-101064).
    Fmoc-leucine-15N
  • HY-101444AR
    PAβN dihydrochloride (Standard) 100929-99-5 98%
    PAβN (dihydrochloride) (Standard) is the analytical standard of PAβN (dihydrochloride) (HY-101444A). This product is intended for research and analytical applications. PAβN dihydrochloride (MC-207110 dihydrochloride) is an efflux pump inhibitor.
    PAβN dihydrochloride (Standard)
  • HY-101634AR
    ABT-072 potassium trihydrate (Standard) 1132940-31-8 98%
    ABT-072 (potassium trihydrate) (Standard) is the analytical standard of ABT-072 (potassium trihydrate) (HY-101634A). This product is intended for research and analytical applications. ABT-072 (potassium trihydrate) is an orally active and potent non-nucleoside HCV NS5B polymerase inhibitor (HCV GT1a EC50=1 nM; HCV GT1b EC50=0.3 nM).
    ABT-072 potassium trihydrate (Standard)
  • HY-101954AR
    Inarigivir ammonium (Standard) 2172788-92-8 98%
    Inarigivir ammonium (Standard) is the analytical standard of Inarigivir ammonium (HY-101954A). This product is intended for research and analytical applications. Inarigivir (ORI-9020) ammonium is a dinucleotide antiviral drug that can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir (ORI-9020) ammonium acts as a RIG-I (Retinoic acid-inducible gene-I) agonist to activate cellular innate immune responses.
    Inarigivir ammonium (Standard)
Cat. No. Product Name / Synonyms Application Reactivity