2-Acetylthiophene thiosemicarbazone
2-Acetylthiophene thiosemicarbazone is an antibacterial agent. 2-Acetylthiophene thiosemicarbazone exhibits anticancer activity, with an IC50 value of 8.6 μM against HT-29 cells.
For research use only. We do not sell to patients.
- CAS No.: 5351-71-3
- Formula: C7H9N3S2
- Molecular Weight:199.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
6.1 μM
Compound: 5
|
Inhibition of alpha-MSH-induced melanin production in mouse B16 cells after 3 days
Inhibition of alpha-MSH-induced melanin production in mouse B16 cells after 3 days
|
[PMID: 21601449] |
| HEK-293T | CC50 |
<100 μM
Compound: 46; SSAA09E1
|
Cytotoxicity against human HEK293T cells by XTT assay
Cytotoxicity against human HEK293T cells by XTT assay
|
[PMID: 33486200] |
| HEK-293T | EC50 |
6.4 μM
Compound: 46; SSAA09E1
|
Inhibition of SARS-COV pseudotyped virus infection in HEK293T cells assessed as reduction in viral replication measured after 48 hrs by ELISA assay
Inhibition of SARS-COV pseudotyped virus infection in HEK293T cells assessed as reduction in viral replication measured after 48 hrs by ELISA assay
|
[PMID: 33486200] |
Chemical Information
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CAS No. 5351-71-3
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Molecular Weight 199.30
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Formula C7H9N3S2
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SMILES
S=C(N/N=C(C)/C1=CC=CS1)N
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Synonyms
ATTSC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)