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Cat. No.: HY-W983893

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7-Hydroxytropolone

Name: 7-Hydroxytropolone
Brand: MedChemExpress
SKU: HY-W983893
Availability: PreOrder

(Synonyms: 3-Hydroxytropolone)

7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic with anti-Gram-positive bacteria, negative bacteria, yeast and fungi activity, and has the effect of inhibiting 2''-O-Adenylyltransferase.

For research use only. We do not sell to patients.

CAS No.: 34777-04-3
Formula: C₇H₆O₃
Molecular Weight:138.12

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

7-Hydroxytropolone Chemical Structure

CAS No.: 34777-04-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic with anti-Gram-positive bacteria, negative bacteria, yeast and fungi activity, and has the effect of inhibiting 2''-O-Adenylyltransferase^[1].

All Antibiotic Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
B16	IC₅₀	2.2 μM Compound: alpha-HT	Cytotoxicity against mouse B16 cells Cytotoxicity against mouse B16 cells	[PMID: 25089179]
MRC5	IC₅₀	1.7 μM Compound: alpha-HT	Cytotoxicity against human MRC5 cells Cytotoxicity against human MRC5 cells	[PMID: 25089179]

Chemical Information

CAS No. 34777-04-3
Molecular Weight 138.12
Formula C₇H₆O₃
SMILES

O=C1C=CC=CC(O)=C1O
Synonyms

3-Hydroxytropolone
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhen Jiang, et al. 7-Hydroxytropolone produced and utilized as an iron-scavenger by Pseudomonas donghuensis. Biometals. 2016 Oct;29(5):817-26. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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7-Hydroxytropolone

All Antibiotic Isoforms