Parvaquone
Parvaquone is an antiparasite agent with an in vitro ED50 of 0.006 mg/L. Parvaquone reduces the proportion of Theileria parva schizont-infected cells. Parvaquone can be used for the research of east coast fever (Theileria parva infection).
For research use only. We do not sell to patients.
- CAS No.: 4042-30-2
- Formula: C16H16O3
- Molecular Weight:256.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Biological Activity
Description
In Vitro
Parvaquone (Compound 43) (48 h) potently inhibits Theileria parva schizont-infected cell populations in vitro, with an ED50 of 0.006 mg/L after 48 h of incubation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 4042-30-2
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Molecular Weight 256.30
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Formula C16H16O3
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SMILES
O=C1C(O)=C(C(=O)C=2C=CC=CC12)C3CCCCC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Parvaquone Related Classifications
HY-W856920 Related Classifications
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