2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0586
    Norisoboldine 23599-69-1 99.65%
    Norisoboldine is an orally active natural aryl hydrocarbon receptor (AhR) agonist. Norisoboldine, as a major isoquinoline alkaloid present in Radix Linderae, can be used for the research of Rheumatoid arthritis and Ulcerative colitis.
    Norisoboldine
  • HY-N0813
    Anemarsaponin E 136565-73-6 99.15%
    Anemarsaponin E is extracted from Anemarrhena asphodeloides Bunge and has anti-inflammatory activity.
    Anemarsaponin E
  • HY-N0860
    Schisantherin E 64917-83-5 99.89%
    Schisantherin E is a natural compound isolated from the active fraction of the fruits of Schisandra sphenanthera Rehd. et Wils.
    Schisantherin E
  • HY-N0926
    Columbamine 3621-36-1 ≥98.0%
    Columbamine (Columbamin; Dehydroisocorypalmine) is an organic heterotetracyclic alkaloid extracted from plants. Columbamine is a metabolite of Berberine (HY-N0716). Columbamine inhibits the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 30.6 µM). Columbamine induces apoptosis in cancer cells. Columbamine can be used for antioxidant, anti-inflammatory, antitumor, antifungal, antiparasite, hepatoprotective, neuroprotective, hypolipidemic and hypoglycemic study.
    Columbamine
  • HY-N1089
    Vincosamide 23141-27-7 99.72%
    Vincosamide, an alkaloid from Psychotria leiocarpa extract, inhibits the acetylcholinesterase (AChE) activity with anti-inflammatory activity.
    Vincosamide
  • HY-N1145
    Tokinolide B 112966-16-2 98.44%
    Tokinolide B is isolated from the rhizomes of Ligusticum porter.
    Tokinolide B
  • HY-N1439
    Methyl gypsogenin-3-O-glucuronide 96553-02-5 99.89%
    Methyl gypsogenin-3-O-glucuronide (Gypsogenin-3-O-(6-O-methyl)-glucoside) is a ubiquitous saponin precursor in plants of the genus Gypsophila.
    Methyl gypsogenin-3-O-glucuronide
  • HY-N1524
    Quinovic acid 465-74-7
    Quinovic acid is triterpene. Quinovic acid can ameliorate the Amyloid-β burden, p53 expression and cholesterol accumulation by deterring the oxidative stress through upregulating the Nrf2/HO-1 pathway. Quinovic acid can induce cancer cells apoptosis by upregulating death receptor 5 (DR5). Quinovic acid can be used for the researches of cancer, inflammation, metabolic and neurological disease, such as lung cancer and Alzheimer’s disease (AD).
    Quinovic acid
  • HY-N1904
    4′-Hydroxywogonin 57096-02-3 98.22%
    4′-Hydroxywogonin (8-Methoxyapigenin), a flavonoid, could be isolated from a variety of plants including Scutellaria barbata and Verbena littoralis. 4′-Hydroxywogonin has anti-inflammatory activity via TAK1/IKK/NF-κB, MAPKs and PI3/AKT signaling pathways. 4′-Hydroxywogonin inhibits angiogenesis by disrupting PI3K/AKT signaling. 4′-Hydroxywogonin inhibits cell proliferation and induces apoptosis.
    4′-Hydroxywogonin
  • HY-N2151
    Rhodojaponin II 26116-89-2 99.90%
    Rhodojaponin II is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory activity.
    Rhodojaponin II
  • HY-N2222
    Epigomisin O 73036-31-4 99.60%
    Epigomisin O is isolate from the fruits of Schisandra plants.
    Epigomisin O
  • HY-N2235
    Gomisin O 72960-22-6 99.77%
    Gomisin O is isolated from the fruits of Schizandra chinensis.
    Gomisin O
  • HY-N2286
    Kushenol I 99119-69-4 99.74%
    Kushenol I is a natural compound isolated from the roots of Sophora flavescens.
    Kushenol I
  • HY-N2400
    Rehmannioside C 81720-07-2 99.47%
    Rehmannioside C is an iridoid glucoside isolated from Radix Rehmanniae Praeparata.
    Rehmannioside C
  • HY-N2401
    Baldrinal 18234-46-3 99.60%
    Baldrinal is derived from the extracts of valerian rhizomes and roots, inhibits autonomic activity, and has anti-inflammatory effects.
    Baldrinal
  • HY-N2503
    Ginsenoside F4 181225-33-2 98.54%
    Ginsenoside F4 (GF4), ginseng saponinis, isolated from notoginseng or red ginseng. Ginsenoside F4 (GF4) has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis. Ginsenoside F4 (GF4) inhibits matrix metalloproteinase 13 (MMP 13) expression in IL-1β-treated chondrocytes and blocks cartilage breakdown in rabbit cartilage tissue culture, shows therapeutic potential for preventing cartilage collagen matrix breakdown in diseased tissues.
    Ginsenoside F4
  • HY-N2504
    Ginsenoside Rk2 364779-14-6 99.25%
    Ginsenoside Rk2 is a dammarane glycoside isolated from the processed ginseng (SG; Sun Ginseng).
    Ginsenoside Rk2
  • HY-N2603
    Saikosaponin H 91990-63-5 99.87%
    Saikosaponin H is a saikosaponin derived from the herb Radix bupleuri.
    Saikosaponin H
  • HY-N2807
    Acanthoside B 7374-79-0 99.49%
    Acanthoside B is a potential bioactive lignan with anti-inflammatory and anti-amnesic activities. Acanthoside B can be used for alzheimer's disease and lung inflammation research
    Acanthoside B
  • HY-N2855
    Alphitolic acid 19533-92-7
    Alphitolic acid (Aophitolic acid) is an anti-inflammatory triterpene could found in quercus aliena. Alphitolic acid blocks Akt–NF-κB signaling to induce apoptosis. Alphitolic acid induces autophagy. Alphitolic acid has anti-inflammatory activity and down-regulates the NO and TNF-α production. Alphitolic acid can be used for cancer and inflammation research.
    Alphitolic acid
Cat. No. Product Name / Synonyms Application Reactivity