2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-156693
    MTvkPABC-P5 3027976-10-6 98%
    MTvkPABC-P5d, a TLR7 agonist, is an immune stimulant. MTvkPABC-P5d can be used for synthesis of immune-stimulating antibody conjugates (ISACs).
    MTvkPABC-P5
  • HY-157194
    RL-6-Me-7-OH 2184-54-5
    RL-6-Me-7-OH is a hapten that activates human and mouse MAIT cells (EC50 = 25 µM). RL-6-Me-7-OH can be combined with carrier proteins and used in antigen design. RL-6-Me-7-OH can be used in inflammation and immunity research.
    RL-6-Me-7-OH
  • HY-157329
    AD16 311315-04-5 98%
    AD16 (Acetamide) is a LINE-1 retrotransposon endonuclease inhibitor with the IC50 of 4.7 μM. AD16 (Acetamide) reduce LINE-1 retrotransposition, L1-induced DNA damage, and inflammation reinforced by L1 in senescent cells.
    AD16
  • HY-157348
    Lauryl Sulfate Tryptose Broth
    Lauryl Sulfate Tryptose Broth can be used for preparation of selective enrichment broth.
    Lauryl Sulfate Tryptose Broth
  • HY-157728
    ML307 3058650-52-2 99.10%
    ML307 is a potent, sub-micromolar, first-in-class Ubc13 enzyme activity inhibitor with an IC50 of 781 nM. ML307 has the potential for immunomodulation and inflammation research.
    ML307
  • HY-157807
    Prostaglandin E2-biotin 2641624-60-2 ≥99.0%
    Prostaglandin E2-biotin is a prostaglandin analog. Prostaglandin E2-biotin can be used for research of Nurr1-related disease, such as cancer and autoimmune disease.
    Prostaglandin E2-biotin
  • HY-157992
    LM-021 1022282-98-9 98.27%
    LM-021 is a coumarin-chalcone derivative with anti-aggregatory, antioxidant, neuroprotective and anti-inflammatory properties which suppresses nitric oxide (NO), IL-1β, IL-6, TNF-α production, CD68 antigen (CD68) and histocompatibility-2 (MHCII) expression. LM-021 also attenuates the increase of caspase 1 activity, lactate dehydrogenase release and ROS level. LM-021 can be used for neurological research.
    LM-021
  • HY-158204
    CNB-001 1019110-87-2 98%
    CNB-001 is a potent and orally active 5-lipoxygenase (5-LOX) inhibitor. CNB-001 can decreases 5-LOX expression and increase proteasome activity. CNB-001 can inhibit accumulation of soluble Amyloid-β and ubiquitinated aggregated proteins. CNB-001 can inhibit apoptosis, ROS production and stabilize mitochondrial membrane potential. CNB-001 can reduce insulin resistance and increase glucose uptake. CNB-001 also exhibits anti-ischemic, anti-inflammatory effects. CNB-001 can be used for the researches of inflammation, neurological and metabolic disease, such as Alzheimer's disease, stroke and diabetes.
    CNB-001
  • HY-158280
    Streptomycin/KLH
    Streptomycin/KLH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Streptomycin/KLH
  • HY-158286
    Streptomycin/OVA
    Streptomycin/OVA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Streptomycin/OVA
  • HY-158292
    Digoxin-OVA
    Digoxin-OVA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Digoxin-OVA
  • HY-158403
    METTL3-IN-7 98%
    METTL3-IN-7 (7460-0250) is a potent METTL3 inhibitor. METTL3-IN-7 strongly ameliorates Dextran sulfate sodium salt (DSS) (HY-116282C)-induced colitis. METTL3-IN-7 can be used Inflammatory bowel disease (IBD) research.
    METTL3-IN-7
  • HY-159827
    Cenacitinib 2641636-52-2 98.08%
    Cenacitinib is a potent Janus kinase inhibitor. Cenacitinib shows anti-inflammatory activity.
    Cenacitinib
  • HY-159886
    MG-C-30 877164-43-7
    MG-C-30 is an orally active agonist for CD27 with an EC50 of 0.84 μM. MG-C-30 activates NK cells and T cell co-stimulatory signals, and enhances immune response. MG-C-30 exhibits antitumor efficacy in mouse EG7-OVA model.
    MG-C-30
  • HY-160040
    Cobitolimod 1226822-98-5
    Cobitolimod is a DNA oligonucleotide agonist of TLR-9 with anti-inflammatory activity. Cobitolimod suppresses Th17 cells and induces anti-inflammatory FoxP3 and IL-10 expression, inhibiting the IL-17 signaling pathway.
    Cobitolimod
  • HY-160073
    Florensocatib 2762114-61-2 98%
    Florensocatib (compound 1) is a potent inhibitor of DPP1. Florensocatib can used in study bronchiectasis.
    Florensocatib
  • HY-160097
    AXC-666 313350-30-0 99.75%
    AXC-666, an immune agonist, is a Imiquimod (HY-B0180) derivative.
    AXC-666
  • HY-160169
    Necrosis inhibitor 2 2258671-03-1 98.28%
    Necrosis inhibitor 2 (Compound B19) is a cell necrosis inhibitor. Necrosis inhibitor 2 can be used to study diseases related to the necrosis pathway, including inflammation, tumors, metabolic diseases and neurodegenerative diseases.
    Necrosis inhibitor 2
  • HY-160179
    Glucocorticoid receptor agonist-4 2842165-72-2 99.80%
    Glucocorticoid receptor agonist-4 (Compound Preparation 5) is a glucocorticoid receptor agonist that can be conjugated to TNF-α antibodies for the study of autoimmune and inflammatory diseases.
    Glucocorticoid receptor agonist-4
  • HY-160181
    INX-SM-3 2734877-96-2 99.50%
    INX-SM-3 is a novel glucocorticosteroid . INX-SM-3 can be used as a glucocorticosteroid-linker connected to ADCs.
    INX-SM-3
Cat. No. Product Name / Synonyms Application Reactivity