2. Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. JAK
  4. Cenacitinib

Cenacitinib is a potent Janus kinase inhibitor. Cenacitinib shows anti-inflammatory activity.

For research use only. We do not sell to patients.

Cenacitinib

Cenacitinib Chemical Structure

CAS No. : 2641636-52-2

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Based on 1 publication(s) in Google Scholar

Cenacitinib Related Antibodies

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Description

Cenacitinib is a potent Janus kinase inhibitor. Cenacitinib shows anti-inflammatory activity[1].

Molecular Weight

431.40

Formula

C19H19F2N7O3
CAS No.
Appearance

Solid

Color

Gray to brown

SMILES

F[C@@H](C1)[C@@H]1NC(NC2=C3N(N=C2)C(NC)=CC(NC4=C5C(OCCO5)=CC(F)=C4)=N3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (23.18 mM; ultrasonic and warming and adjust pH to 4 with 1 M HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3180 mL 11.5902 mL 23.1803 mL
5 mM 0.4636 mL 2.3180 mL 4.6361 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3180 mL 11.5902 mL 23.1803 mL 57.9509 mL
5 mM 0.4636 mL 2.3180 mL 4.6361 mL 11.5902 mL
10 mM 0.2318 mL 1.1590 mL 2.3180 mL 5.7951 mL
15 mM 0.1545 mL 0.7727 mL 1.5454 mL 3.8634 mL
20 mM 0.1159 mL 0.5795 mL 1.1590 mL 2.8975 mL
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Cenacitinib Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cenacitinib2641636-52-2JAKJanus kinaseanti-inflammatoryInhibitorinhibitorinhibit

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