2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N3846
    Ergosterol peroxide glucoside 140447-22-9 98%
    Ergosterol peroxide glucoside is an Ergosterol derivative.
    Ergosterol peroxide glucoside
  • HY-N3848
    Ermanin 20869-95-8 99.47%
    Ermanin is a flavonoid isolated from Tanacetum microphyllum. Ermanin potently inhibits iNOS, COX-2 activities, and inhibits platelet aggregation. Ermanin has anti-inflammatory, anti-tuberculous and anti-viral/bacterial properties.
    Ermanin
  • HY-N3866
    Esculentic acid 103974-74-9 98%
    Esculentic acid is a selective COX-2 inhibitor and has anti-inflammatory effect. Esculentic acid is a pentacyclic triterpenoid that can be extracted from the Chinese herb Phytolacca esculenta.
    Esculentic acid
  • HY-N3891
    Fargesone A 116424-69-2 98%
    Fargesone A is a potent and selective FXR agonist. Fargesone A shows anti-inflammatory activity.
    Fargesone A
  • HY-N4022
    Hyuganin D 77331-76-1 98%
    Hyuganin D (Isobocconin) is a Coumarin (HY-N0709) constituent that substantially inhibits LPS (HY-D1056)-induced NO production in mouse peritoneal macrophages.
    Hyuganin D
  • HY-N4024
    Hyptadienic acid 128397-09-1
    Hyptadienic acid is a triterpene acid that can be isolated from the leaves of Perilla frutescens. Hyptadienic acid inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice with an ID50 value of 0.13 mg/ear. Hyptadienic acid can be used for the research of inflammation.
    Hyptadienic acid
  • HY-N4061
    Hedycoronen A 1383441-73-3 98%
    Hedycoronen A has inhibitory activity on the IL-6, IL-12 p40, and TNF-α production in LPS-Stimulated BMDCs, with IC50s of 9.1 μM, 5.6 μM, and 46.0 μM. Hedycoronen A can be isolated from Hedychium coronarium.
    Hedycoronen A
  • HY-N4080
    Cyclobuxine D 2241-90-9 98%
    Cyclobuxine D is a steroidal alkaloid extracted from Buxus microphylla. Cyclobuxine D has a significant bradycardic effect in the rat heart and an inhibitory action on acetylcholine and Ba++−induced contraction of the longitudinal muscle isolated from the rabbit jejunum.
    Cyclobuxine D
  • HY-N4128
    4''-methyloxy-Daidzin 1195968-02-5 98%
    4''-methyloxy-Daidzin (Daidzein 7-O-Β-D-glucoside 4''-O-methylate), an isoflavone methyl-glycoside, is isolated from Cordyceps militaris grown on germinated soybeans. Isoflavones possess immunomodulating and antiallergic activities.
    4''-methyloxy-Daidzin
  • HY-N4129
    4''-methyloxy-Genistin 950910-16-4 98%
    4''-methyloxy-Genistin, an isoflavone methyl-glycoside, is isolated from Cordyceps militaris grown on germinated soybeans. Isoflavones possess immunomodulating and antiallergic activities.
    4''-methyloxy-Genistin
  • HY-N4145
    Procyanidin A3 86631-39-2 98%
    Procyanidin A3 (Cinnamtannin A3; Cinnamtannin II) is a sub class of Proanthocyanidins (HY-N0794). Proanthocyanidin are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancer agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy.
    Procyanidin A3
  • HY-N4215
    11(α)-Methoxysaikosaponin F 104109-37-7 99.51%
    11(α)-Methoxysaikosaponin F is a triterpenoid saponin isolated from Bupleurum marginatum Wall.ex DC(ZYCH) which is a promising therapeutic for liver fibrosis. 11(α)-Methoxysaikosaponin F has an IC50 of 387.7 nM with viability of hepatic stellate cells-T6 (HSCs-T6). Triterpenoid saponins have numerous targets, important network positions, and strong inhibitory activity.
    11(α)-Methoxysaikosaponin F
  • HY-N4230
    Clematomandshurica saponin B 916649-91-7 98%
    Clematomandshurica saponins B shows significant inhibitory activity on cyclooxygenase-2 (IC50=2.58 mM).
    Clematomandshurica saponin B
  • HY-N4234
    Angelol K 169736-93-0 98%
    Angelol K is a natural product from Chinese angelica.
    Angelol K
  • HY-N4235
    Angelol B 83156-04-1 98%
    Angelol B is a coumarin isolated from the roots of Angelica pubescens f. biserrata, which is passive diffusion as the dominating process in Caco-2 cell monolayer model.
    Angelol B
  • HY-N4264
    Vinaginsenoside R3 156012-92-9 98%
    Vinaginsenoside R3 is a saponin composition of roots of Panax ginseng. Ginsengs have been not only used as therapeutic agents with tonic, anti-fatigue, and anti-gastric ulcer effect but also marketed as dietary supplements and raw materials of health food.
    Vinaginsenoside R3
  • HY-N4278
    Huangjiangsu A 1026020-27-8 98%
    Huangjiangsu A, pseudoprotodioscin, methyl protobioside, protodioscin, and protodeltonin, isolated from D. villosa. Huangjiangsu A has hepatoprotective potential against H2O2-induced cytotoxicity and ROS generation and could be promising as potential therapeutic agents for liver diseases.
    Huangjiangsu A
  • HY-N5045
    Jionoside A1 120444-60-2 98.58%
    Jionoside A1 isolated from Radix Rehmanniae Praeparata displays dose dependent immune-enhancement activity and possesses moderate protective activities on H2O2-treated SH-SY5Y cells.
    Jionoside A1
  • HY-N5046
    27-O-Acetyl-withaferin A 1214886-35-7 98%
    27-O-Acetyl-withaferin A is found in Withania aristata.
    27-O-Acetyl-withaferin A
  • HY-N5051
    25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside 125225-63-0 98%
    25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside shows inhibitory activity of neutrophil respiratory burst stimulated by PMA(phorbol myristate acetate).
    25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside
Cat. No. Product Name / Synonyms Application Reactivity