Hyptadienic acid

Cat. No.: HY-N4024 Purity: 93.0%: Data Sheet
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Hyptadienic acid is a triterpene acid that can be isolated from the leaves of Perilla frutescens. Hyptadienic acid inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice with an ID₅₀ value of 0.13 mg/ear. Hyptadienic acid can be used for the research of inflammation.

For research use only. We do not sell to patients.

Hyptadienic acid Chemical Structure

CAS No. : 128397-09-1

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	Get quote	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	24.68 μM Compound: 32	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 20515057]
A549	IC₅₀	7.4 μM Compound: 37	Anticancer activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Anticancer activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 37146221]
HL-60	IC₅₀	15.48 μM Compound: 32	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 20515057]
MCF7	IC₅₀	> 10 μM Compound: 37	Anticancer activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 37146221]
MCF7	IC₅₀	> 40 μM Compound: 32	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 20515057]
MDA-MB-231	IC₅₀	> 10 μM Compound: 37	Anticancer activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Anticancer activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 37146221]
NCI-H1975	IC₅₀	> 10 μM Compound: 37	Anticancer activity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Anticancer activity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 37146221]
SMMC-7721	IC₅₀	21.01 μM Compound: 32	Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay	[PMID: 20515057]
SW480	IC₅₀	10.86 μM Compound: 32	Cytotoxicity against human SW480 cells after 48 hrs by MTT assay Cytotoxicity against human SW480 cells after 48 hrs by MTT assay	[PMID: 20515057]

Molecular Weight

470.68

Formula

C₃₀H₄₆O₄

CAS No.

128397-09-1

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12C([C@@]3([H])[C@](C(O)=O)(CC[C@@H](C)[C@]3(O)C)CC2)=CC[C@@]4([H])[C@]1(CC[C@]5([H])[C@@]4(C(CO)=CC5(C)C)C)C

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Purity: 93.0%

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Data Sheet (270 KB) SDS (252 KB)

COA (254 KB)

Handling Instructions (2659 KB)

References

[1]. Banno N, et al. Triterpene acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effects. Biosci Biotechnol Biochem. 2004 Jan;68(1):85-90. [Content Brief]