Hyuganin D
Hyuganin D (Isobocconin) is a Coumarin (HY-N0709) constituent that substantially inhibits LPS (HY-D1056)-induced NO production in mouse peritoneal macrophages.
For research use only. We do not sell to patients.
- CAS No.: 77331-76-1
- Formula: C20H22O7
- Molecular Weight:374.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | IC50 |
>100 μM
Compound: 5
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Inhibitory activity against D-GalN-induced cytotoxicity in rat hepatocytes
Inhibitory activity against D-GalN-induced cytotoxicity in rat hepatocytes
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[PMID: 9873511] |
Chemical Information
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CAS No. 77331-76-1
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Molecular Weight 374.38
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Formula C20H22O7
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SMILES
CC(C)C(O[C@@H]1C2=C(O3)C(C=CC3=O)=CC=C2OC(C)(C)[C@@H]1OC(C)=O)=O
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Synonyms
Isobocconin; Seravschanin
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yoshikawa M, et al. Inhibitory effects of coumarin and acetylene constituents from the roots of Angelica furcijuga on D-galactosamine/lipopolysaccharide-induced liver injury in mice and on nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages. Bioorg Med Chem. 2006 Jan 15;14(2):456-63. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hyuganin D Related Classifications
HY-N4022 Related Classifications
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