2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1971S1
    Deltamethrin-d6 2483831-10-1 98%
    Deltamethrin-d6 (Decamethrin-d6) is deuterium labeled Deltamethrin. Deltamethrin (Decamethrin) is an orally active synthetic pyrethroid insecticide. Deltamethrin induces oxidative stress and results in inflammation and apoptosis via inhibiting Nrf2/HO-1 pathway. Deltamethrin has an anticancer effect by inducing apoptosis. Deltamethrin can be used extensively in pest control.
    Deltamethrin-d6
  • HY-B2176AR
    ATP disodium trihydrate (Standard) 51963-61-2 98%
    ATP (disodium trihydrate) (Standard) is the analytical standard of ATP (disodium trihydrate). This product is intended for research and analytical applications. ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation.
    ATP disodium trihydrate (Standard)
  • HY-B2176BR
    ATP dimagnesium (Standard) 74804-12-9
    ATP (dimagnesium) (Standard) is the analytical standard of ATP (dimagnesium). This product is intended for research and analytical applications. ATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo. ATP dimagnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dimagnesium is an important endogenous signaling molecule in immunity and inflammation.
    ATP dimagnesium (Standard)
  • HY-D0205AR
    Carbocisteine (Standard) 638-23-3 98%
    Carbocisteine (Standard) is the analytical standard of Carbocisteine. This product is intended for research and analytical applications. Carbocisteine, a mucolytic agent, can be used for the research of chronic obstructive pulmonary disease (COPD).
    Carbocisteine (Standard)
  • HY-F0002AR
    NADP disodium salt (Standard) 24292-60-2 98%
    NADP (disodium salt) (Standard) is the analytical standard of NADP (disodium salt). This product is intended for research and analytical applications. NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes.
    NADP disodium salt (Standard)
  • HY-I0447AR
    Sodium 4-aminosalicylate dihydrate (Standard) 6018-19-5 98%
    Sodium 4-aminosalicylate (dihydrate) (Standard) is the analytical standard of Sodium 4-aminosalicylate (dihydrate). This product is intended for research and analytical applications. Sodium 4-aminosalicylate dihydrate (4-Aminosalicylic acid sodium salt dihydrate) is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. Sodium 4-aminosalicylate dihydrate exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). Sodium 4-aminosalicylate dihydrate is orally active.
    Sodium 4-aminosalicylate dihydrate (Standard)
  • HY-N0001S2
    (-)-Epicatechin-13C3 98%
    (-)-Epicatechin-13C3 ((-)-Epicatechol-13C3) is 13C labeled (-)-Epicatechin. (-)-Epicatechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.
    (-)-Epicatechin-13C3
  • HY-N0005S1
    Curcumin-d3 98%
    Curcumin-d3 (Diferuloylmethane-d3 ) is deuterium labeled Curcumin (HY-N0005). Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin is a photosensitizer against microorganisms. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
    Curcumin-d3
  • HY-N0092S4
    Inosine-13C3 98%
    Inosine-13C3 is a 13C-labeled Inosine that can be used in pharmacokinetic studies of Inosine. Inosine is an agonist of adenosine receptors A1R and A2AR with anti-inflammatory immunomodulatory, antinociceptive and neuroprotective effects.
    Inosine-13C3
  • HY-N0114AR
    (±)-Evodiamine (Standard) 518-18-3 98%
    (±)-Evodiamine (Standard) is the analytical standard of (±)-Evodiamine. This product is intended for research and analytical applications. (±)-Evodiamine, a quinazolinocarboline alkaloid, is a Top1 inhibitor. Evodiamine exhibits anti-inflammatory, antiobesity, and antitumor effects. (±)-Evodiamine inhibits the proliferation of a wide variety of tumor cells by inducing their apoptosis.
    (±)-Evodiamine (Standard)
  • HY-N0363AR
    (+)-Columbianetin acetate (Standard) 23180-65-6
    (+)-Columbianetin acetate (Standard) is the analytical standard of (+)-Columbianetin acetate. This product is intended for research and analytical applications. (S)-Columbianetin acetate is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity.
    (+)-Columbianetin acetate (Standard)
  • HY-N0523AR
    Gallic acid hydrate (Standard) 5995-86-8 99.86%
    Gallic acid (hydrate) (Standard) is the analytical standard of Gallic acid (hydrate). This product is intended for research and analytical applications. Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2). Gallic acid hydrate has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities.
    Gallic acid hydrate (Standard)
  • HY-N0658AR
    DL-Threonine (Standard) 80-68-2
    DL-Threonine (Standard) is the analytical standard of DL-Threonine. This product is intended for research and analytical applications. DL-Threonine, an essential amino acid, is a precursor of Glycine (HY-Y0966). DL-Threonine has the potential for the study of hypostatic leg ulceration.
    DL-Threonine (Standard)
  • HY-N0666CR
    L-Aspartic aicd sodium (Standard) 3792-50-5
    L-Aspartic aicd sodium is an amino acid. L-Aspartic aicd sodium is commonly used for preparing prodrugs to target colon and cecal tissues. L-Aspartic aicd sodium commonly used in the study of inflammatory conditions.
    L-Aspartic aicd sodium (Standard)
  • HY-N0666DR
    L-Aspartic aicd disodium (Standard) 5598-53-8
    L-Aspartic acid disodium is an amino acid. L-Aspartic acid disodium is commonly used for preparing prodrugs to target colon and cecal tissues. L-Aspartic acid disodium commonly used in the study of inflammatory conditions.
    L-Aspartic aicd disodium (Standard)
  • HY-N0761AR
    trans-Isoferulic acid (Standard) 25522-33-2 98%
    trans-Isoferulic acid (Standard) is the analytical standard of trans-Isoferulic acid. This product is intended for research and analytical applications. trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity.trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1).
    trans-Isoferulic acid (Standard)
  • HY-N0779AR
    Silybin (Standard) 802918-57-6 98%
    Silybin (Standard) is the analytical standard of Silybin. This product is intended for research and analytical applications. Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity.
    Silybin (Standard)
  • HY-N0805AR
    Alisol B (Standard) 18649-93-9
    Alisol B (Standard) is the analytical standard of Alisol B (HY-N0805A). This product is intended for research and analytical applications. Alisol B is a triterpene with diverse biological activities. Alisol B binds human soluble epoxide hydrolase (sEH) with a Ki of 5.97 μM and reduces sEH activity. Alisol B inhibits RANKL-induced JNK phosphorylation, NFATc1 and c-Fos expression, osteoclast formation, mature osteoclast pit-forming and actin ring activity, and SERCA pump activity. Alisol B induces calcium mobilization, CaMKK-AMPK-mTOR pathway activation, autophagic flux, autophagosome formation, G1 phase cell cycle arrest, endoplasmic reticulum stress, unfolded protein responses, and cancer cell apoptosis. Alisol B can be used for the research of hypercalcemia, osteoporosis, rheumatoid arthritis, periodontitis, acute kidney injury, and breast cancer.
    Alisol B (Standard)
  • HY-N10821A
    Blestriarene A 126721-53-7 98%
    Blestriarene A ((-)-Blestriarene A) is a active product that can beextracts from the tubers of Gymnadenia conopsea. Blestriarene A shows an antiallergic effect.
    Blestriarene A
  • HY-N11822A
    Glucoraphasatin potassium 245550-64-5 98%
    Glucoraphasatin potassium is potassium salt of Glucoraphasatin (HY-N11822). Glucoraphasatin is an atypical and orally active glucosinolate found in cruciferous vegetables, including Raphanus sativus. Glucoraphasatin exhibits anti-inflammation and anti-oxidant activity. Glucoraphasatin can affect phase I metabolic enzymes activity. Glucoraphasatin can be converted by the plant enzyme myrosinase into isothiocyanates and shows cytotoxic to cancer cells. Glucoraphasatin can be used for the researches of cancer and inflammation, such as colon cancer.
    Glucoraphasatin potassium
Cat. No. Product Name / Synonyms Application Reactivity